STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61251.1Protein serine/threonine phosphatase with extracellular sensor; PFAM: HAMP domain; Stage II sporulation protein E (SpoIIE); COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR010822:IPR001932; KEGG: sta:STHERM_c09530 HAMP domain-containing protein; PFAM: Sporulation stage II, protein E C-terminal; HAMP linker domain; SMART: Protein phosphatase 2C-related; HAMP linker domain; SPTR: Protein serine/threonine phosphatase. (1530 aa)    
Predicted Functional Partners:
AEJ60332.1
Anti-sigma-factor antagonist; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR002645:IPR003658; KEGG: sta:STHERM_c00450 anti-anti-sigma factor; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist.
 
 
 0.913
AEJ61249.1
Protein of unknown function UPF0164; PFAM: Uncharacterised protein family (UPF0164); InterPro IPR005362:IPR001440:IPR019734; KEGG: sta:STHERM_c09500 hypothetical protein; PFAM: Uncharacterised protein family UPF0164; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Putative uncharacterized protein.
 
     0.909
AEJ61221.1
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
    0.853
AEJ61214.1
KEGG: sta:STHERM_c09150 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.852
AEJ61215.1
PFAM: Flagellar hook-length control protein FliK; InterPro IPR001635; KEGG: sta:STHERM_c09160 hypothetical protein; PFAM: Flagellar hook-length control protein; SPTR: Flagellar hook-length control protein-like, C-terminal domain.
 
    0.812
AEJ61250.1
Hypothetical protein; InterPro IPR011717; KEGG: sta:STHERM_c09520 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.811
AEJ61208.1
PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE; COGs: COG1677 Flagellar hook-basal body protein; InterPro IPR001624; KEGG: sta:STHERM_c09090 flagellar hook-basal body complex protein FliE; PFAM: Flagellar hook-basal body complex protein FliE; SPTR: Flagellar hook-basal body complex subunit FliE; TIGRFAM: Flagellar hook-basal body complex protein FliE.
 
    0.797
AEJ61995.1
KEGG: sta:STHERM_c16750 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.776
AEJ60715.1
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterProIPR000014:IPR000160:IPR001789:IPR001633:IPR 013767; KEGG: sta:STHERM_c04670 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; PAS fold; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclas [...]
  
  
 0.775
AEJ60625.1
KEGG: sta:STHERM_c03720 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.773
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.