STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61253.1KEGG: sta:STHERM_c09550 hypothetical protein; SPTR: Putative uncharacterized protein. (111 aa)    
Predicted Functional Partners:
AEJ61255.1
Protein of unknown function DUF192; PFAM: Uncharacterized ACR, COG1430; COGs: COG1430 conserved hypothetical protein; InterPro IPR003795; KEGG: sta:STHERM_c09570 exported protein; PFAM: Protein of unknown function DUF192; SPTR: Exported protein; manually curated.
       0.791
AEJ60289.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 
 0.786
AEJ61252.1
KEGG: sta:STHERM_c09540 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ61254.1
KEGG: sta:STHERM_c09560 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.768
AEJ61250.1
Hypothetical protein; InterPro IPR011717; KEGG: sta:STHERM_c09520 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.645
AEJ61251.1
Protein serine/threonine phosphatase with extracellular sensor; PFAM: HAMP domain; Stage II sporulation protein E (SpoIIE); COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR010822:IPR001932; KEGG: sta:STHERM_c09530 HAMP domain-containing protein; PFAM: Sporulation stage II, protein E C-terminal; HAMP linker domain; SMART: Protein phosphatase 2C-related; HAMP linker domain; SPTR: Protein serine/threonine phosphatase.
       0.645
AEJ61249.1
Protein of unknown function UPF0164; PFAM: Uncharacterised protein family (UPF0164); InterPro IPR005362:IPR001440:IPR019734; KEGG: sta:STHERM_c09500 hypothetical protein; PFAM: Uncharacterised protein family UPF0164; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Putative uncharacterized protein.
       0.490
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.