STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61261.1ATP-grasp fold domain protein, DUF201-type; PFAM: ATP-grasp domain; COGs: COG0439 Biotin carboxylase; InterPro IPR003806; KEGG: sta:STHERM_c09640 CarB family protein; PFAM: ATP-grasp fold, DUF201-type; SPTR: Putative uncharacterized protein. (536 aa)    
Predicted Functional Partners:
AEJ62455.1
Biotin/lipoyl attachment domain-containing protein; PFAM: HMGL-like; Biotin-requiring enzyme; Conserved carboxylase domain; COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891:IPR000089; KEGG: sta:STHERM_c21570 pyruvate carboxylase, beta chain; PFAM: Biotin/lipoyl attachment; Pyruvate carboxyltransferase; SPTR: Biotin/lipoyl attachment domain-containing protein.
  
 
 0.989
AEJ61581.1
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.883
AEJ61262.1
Cell wall hydrolase/autolysin; PFAM: N-acetylmuramoyl-L-alanine amidase; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: sta:STHERM_c09650 hypothetical protein; PFAM: Cell wall hydrolase/autolysin, catalytic; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: Cell wall hydrolase/autolysin.
       0.811
AEJ61263.1
Hypothetical protein; PFAM: Sporulation and spore germination; KEGG: sta:STHERM_c09660 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.811
AEJ60747.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
   0.789
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
 
 0.780
accA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
  
 
 0.749
AEJ62134.1
Protein of unknown function DUF2225; PFAM: Uncharacterized protein conserved in bacteria (DUF2225); COGs: COG1655 conserved hypothetical protein; InterPro IPR018708; KEGG: sta:STHERM_c18340 hypothetical protein; PFAM: Protein of unknown function DUF2225; SPTR: Putative uncharacterized protein.
 
     0.731
AEJ61208.1
PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE; COGs: COG1677 Flagellar hook-basal body protein; InterPro IPR001624; KEGG: sta:STHERM_c09090 flagellar hook-basal body complex protein FliE; PFAM: Flagellar hook-basal body complex protein FliE; SPTR: Flagellar hook-basal body complex subunit FliE; TIGRFAM: Flagellar hook-basal body complex protein FliE.
  
     0.715
AEJ61258.1
PFAM: Radical SAM superfamily; InterPro IPR007197; KEGG: sta:STHERM_c09600 hypothetical protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein.
 
     0.689
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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