STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61272.1PFAM: HD domain; 7TM-HD extracellular; 7TM receptor with intracellular HD hydrolase; TIGRFAM: uncharacterized domain HDIG; COGs: COG1480 membrane-associated HD superfamily hydrolase; InterPro IPR011621:IPR006674:IPR006675:IPR003607; KEGG: sta:STHERM_c09750 hypothetical protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; Metal-dependent phosphohydrolase, 7TM intracellular region; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: 7TM receptor with intracellular metal dependent phosphohydrolase; TIGRFAM: HDIG. (746 aa)    
Predicted Functional Partners:
ybeY
Metalloprotease ybeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.856
AEJ61271.1
PFAM: PhoH-like protein; COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714; KEGG: sta:STHERM_c09740 PhoH-like protein; PFAM: PhoH-like protein; SPTR: PhoH family protein.
     
 0.815
AEJ61274.1
PFAM: CBS domain; Transporter associated domain; COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR005170; KEGG: sta:STHERM_c09770 hypothetical protein; PFAM: Cystathionine beta-synthase, core; Transporter-associated region; SMART: Cystathionine beta-synthase, core; SPTR: CBS domain containing protein.
       0.811
AEJ61275.1
Tetratricopeptide TPR_2 repeat-containing protein; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR013105:IPR011717:IPR001440:IPR019734; KEGG: sta:STHERM_c09780 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-4; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
   
   0.789
AEJ61269.1
Conserved hypothetical protein CHP00730; PFAM: Possible lysine decarboxylase; TIGRFAM: TIGR00725 family protein; TIGR00730 family protein; COGs: COG1611 Rossmann fold nucleotide-binding protein; InterPro IPR005269; KEGG: sta:STHERM_c09720 hypothetical protein; PFAM: Conserved hypothetical protein CHP00730; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00730; Belongs to the LOG family.
       0.634
AEJ61270.1
PFAM: Protein of unknown function (DUF434); COGs: COG2454 conserved hypothetical protein; InterPro IPR007368; KEGG: sta:STHERM_c09730 hypothetical protein; PFAM: Protein of unknown function DUF434; SPTR: Putative uncharacterized protein.
       0.634
AEJ61276.1
PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR006424; KEGG: sta:STHERM_c09790 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; SPTR: Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: Glyceraldehyde-3-p [...]
       0.570
AEJ61268.1
KEGG: sta:STHERM_c09710 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.554
AEJ61267.1
PFAM: Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839; KEGG: sta:STHERM_c09700 hypothetical protein; PFAM: Aminotransferase, class I/II; SPTR: Aminotransferase class I and II.
       0.424
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
       0.413
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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