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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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AEJ61286.1PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); TIGRFAM: periplasmic serine protease, Do/DeqQ family; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001254:IPR011782:IPR001478; KEGG: sta:STHERM_c09890 periplasmic serine protease DO; PFAM: Peptidase S1/S6, chymotrypsin/Hap; SMART: PDZ/DHR/GLGF; SPTR: Protease Do; TIGRFAM: Peptidase S1C, Do. (488 aa)    
Predicted Functional Partners:
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Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
  
   0.793
AEJ61284.1
Hypothetical protein; PFAM: Tetratricopeptide repeat; KEGG: sta:STHERM_c09870 hypothetical protein; SPTR: Putative uncharacterized protein.
   
 
 0.719
AEJ61281.1
Heat shock protein DnaJ domain protein; PFAM: DnaJ domain; COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623; KEGG: sta:STHERM_c09840 molecular chaperone protein; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Heat shock protein DnaJ domain protein.
  
 
 0.684
AEJ61282.1
PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: SurA N-terminal domain; PPIC-type PPIASE domain; InterPro IPR000297; KEGG: sta:STHERM_c09850 basic membrane protein; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase.
     
 0.677
nusB
NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
  
    0.675
AEJ61280.1
KEGG: sta:STHERM_c09830 hypothetical protein; SPTR: Putative uncharacterized protein.
     
 0.641
AEJ62432.1
Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR001440:IPR013105:IPR019734; KEGG: sta:STHERM_c21310 hypothetical protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
 
 
 0.537
AEJ61247.1
PFAM: Ankyrin repeat; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110; KEGG: sta:STHERM_c09480 ankyrin repeat-containing protein; PFAM: Ankyrin repeat; SMART: Ankyrin repeat; SPTR: Ankyrin.
  
 0.479
AEJ60956.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR001440:IPR013105:IPR019734; KEGG: sta:STHERM_c06620 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
   
 
 0.474
AEJ61279.1
Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
     
 0.444
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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