Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61288.1KEGG: sta:STHERM_c09910 hypothetical protein; SPTR: Putative uncharacterized protein. (211 aa)    
Predicted Functional Partners:
AEJ61287.1
KEGG: sta:STHERM_c09900 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
folD
Bifunctional protein folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.608
AEJ61292.1
PFAM: AICARFT/IMPCHase bienzyme; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR013982; KEGG: sta:STHERM_c09950 phosphoribosylaminoimidazolecarboxamideformyltra nsferase; PFAM: AICARFT/IMPCHase bienzyme, formylation region; SMART: AICARFT/IMPCHase bienzyme, formylation region; SPTR: Phosphoribosylaminoimidazolecarboxamide formyltransferase.
       0.574
folE2
Protein of unknown function DUF198; Converts GTP to 7,8-dihydroneopterin triphosphate.
       0.573
AEJ61291.1
MGS domain protein; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982; KEGG: sta:STHERM_c09940 phosphoribosylaminoimidazolecarboxamideformyltra nsferase; PFAM: MGS-like; AICARFT/IMPCHase bienzyme, formylation region; SPTR: Phosphoribosylaminoimidazolecarboxamide formyltransferase.
       0.572
AEJ61294.1
PFAM: Protein of unknown function (DUF1049); KEGG: sta:STHERM_c09970 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.565
miaB
(Dimethylallyl)adenosine tRNA methylthiotransferase miaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
       0.545
AEJ61295.1
Sporulation domain-containing protein; PFAM: Sporulation related domain; InterPro IPR007730; KEGG: sta:STHERM_c09980 hypothetical protein; PFAM: Sporulation/cell division region, bacteria; SPTR: Sporulation domain-containing protein.
       0.539
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.