STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61296.1KEGG: sta:STHERM_c09990 hypothetical protein; SPTR: Putative uncharacterized protein. (514 aa)    
Predicted Functional Partners:
AEJ61693.1
Flagellar basal-body rod protein FlgF; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgF; fagellar hook-basal body proteins; COGs: COG4786 Flagellar basal body rod protein; InterPro IPR001444:IPR010930:IPR020013:IPR012836; KEGG: sta:STHERM_c07290 flagellar hook-basal body complex protein; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellar basal body rod protein, N-terminal; SPTR: Flagellar hook-basal body complex protein; TIGRFAM: Flagellar basal-body rod FlgF; Fagellar hook-basal body protein, FlgE [...]
   
   0.643
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.568
AEJ61297.1
PFAM: Lyase; Adenylosuccinate lyase C-terminus; COGs: COG0015 Adenylosuccinate lyase; InterPro IPR000362; KEGG: sta:STHERM_c10000 adenylosuccinate lyase; PFAM: Fumarate lyase; SPTR: Fumarate lyase.
       0.561
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
    0.532
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.509
AEJ61426.1
Outer membrane chaperone Skp (OmpH); PFAM: Outer membrane protein (OmpH-like); InterPro IPR005632; KEGG: sta:STHERM_c11240 hypothetical protein; PFAM: Outer membrane chaperone Skp (OmpH); SPTR: Outer membrane chaperone Skp (OmpH).
  
 
 0.484
AEJ61217.1
PFAM: Flagella basal body rod protein; Domain of unknown function (DUF1078); Flagellar basal body protein FlaE; TIGRFAM: fagellar hook-basal body proteins; COGs: COG1749 Flagellar hook protein FlgE; InterPro IPR001444:IPR011491:IPR010930:IPR020013; KEGG: sta:STHERM_c09180 flagellar hook protein; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellar basal body FlaE; Flagellar basal body rod protein, N-terminal; SPTR: Fagellar hook-basal body protein; TIGRFAM: Fagellar hook-basal body protein, FlgE/F/G.
   
 
 0.483
AEJ60430.1
Peptidoglycan-binding lysin domain-containing protein; PFAM: LysM domain; InterPro IPR018392:IPR002482; KEGG: sta:STHERM_c01550 hypothetical protein; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Peptidoglycan-binding lysin domain.
  
  
 0.465
AEJ62118.1
KEGG: sta:STHERM_c17890 hypothetical protein; SPTR: Putative uncharacterized protein.
  
  
 0.465
AEJ61207.1
Flagellar basal-body rod protein FlgC; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgC; COGs: COG1558 Flagellar basal body rod protein; InterPro IPR001444:IPR010930:IPR006299; KEGG: sta:STHERM_c09080 hypothetical protein; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellar basal body rod protein, N-terminal; SPTR: Putative uncharacterized protein; TIGRFAM: Flagellar basal-body rod protein FlgC.
   
   0.459
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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