Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61303.1RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627:IPR013249:IPR014284; KEGG: sta:STHERM_c10060 hypothetical protein; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma factor 70, region 4 type 2; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70. (193 aa)    
Predicted Functional Partners:
AEJ61969.1
KEGG: sta:STHERM_c16480 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.785
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.781
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.780
AEJ61302.1
KEGG: sta:STHERM_c10050 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ62124.1
RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627:IPR013249:IPR014284; KEGG: sta:STHERM_c18250 hypothetical protein; PFAM: RNA polymerase sigma factor 70, region 4 type 2; RNA polymerase sigma-70 region 2; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70.
  
     0.771
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.760
AEJ61301.1
KEGG: sta:STHERM_c10040 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.727
AEJ61524.1
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.701
AEJ61305.1
TIGRFAM: RND family efflux transporter, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR000089:IPR006143; KEGG: sta:STHERM_c10080 efflux transporter, RND family, MFP subunit; PFAM: Biotin/lipoyl attachment; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD.
 
   
 0.624
AEJ61308.1
PFAM: Peptidase family M23; LysM domain; COGs: COG4942 Membrane-bound metallopeptidase; InterPro IPR018392:IPR016047:IPR002482; KEGG: sta:STHERM_c10110 LysM domain/M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Peptidase M23.
 
 
   0.585
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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