Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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AEJ61308.1PFAM: Peptidase family M23; LysM domain; COGs: COG4942 Membrane-bound metallopeptidase; InterPro IPR018392:IPR016047:IPR002482; KEGG: sta:STHERM_c10110 LysM domain/M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Peptidase M23. (265 aa)    
Predicted Functional Partners:
AEJ61262.1
Cell wall hydrolase/autolysin; PFAM: N-acetylmuramoyl-L-alanine amidase; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: sta:STHERM_c09650 hypothetical protein; PFAM: Cell wall hydrolase/autolysin, catalytic; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: Cell wall hydrolase/autolysin.
 
 
 0.769
AEJ61305.1
TIGRFAM: RND family efflux transporter, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR000089:IPR006143; KEGG: sta:STHERM_c10080 efflux transporter, RND family, MFP subunit; PFAM: Biotin/lipoyl attachment; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD.
 
   
 0.695
AEJ61306.1
PFAM: ABC transporter; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c10090 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Transporter; manually curated.
     
 0.643
AEJ61310.1
PFAM: Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase; COGs: COG2096 conserved hypothetical protein; InterPro IPR002779:IPR017858; KEGG: sta:STHERM_c10130 hypothetical protein; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, EutT/PduO type; SPTR: ATP/cobalamin adenosyltransferase; TIGRFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, PduO-type, N-terminal.
       0.641
AEJ61304.1
KEGG: sta:STHERM_c10070 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.631
AEJ61307.1
Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: sta:STHERM_c10100 hypothetical protein; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein.
       0.631
AEJ61702.1
PFAM: Peptidase family M23; LysM domain; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR018392:IPR016047; KEGG: sta:STHERM_c07180 M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SPTR: Peptidase M23.
 
   
 0.600
AEJ61309.1
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.597
AEJ62165.1
PFAM: Peptidase family M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: sta:STHERM_c18630 M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; SPTR: Peptidase M23.
 
   
 0.596
AEJ60948.1
PFAM: Peptidase family M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: sta:STHERM_c06540 M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; SPTR: Peptidase M23.
 
   
 0.594
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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