STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61310.1PFAM: Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase; COGs: COG2096 conserved hypothetical protein; InterPro IPR002779:IPR017858; KEGG: sta:STHERM_c10130 hypothetical protein; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, EutT/PduO type; SPTR: ATP/cobalamin adenosyltransferase; TIGRFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, PduO-type, N-terminal. (182 aa)    
Predicted Functional Partners:
AEJ61309.1
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.762
AEJ60486.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
   
 0.710
AEJ61308.1
PFAM: Peptidase family M23; LysM domain; COGs: COG4942 Membrane-bound metallopeptidase; InterPro IPR018392:IPR016047:IPR002482; KEGG: sta:STHERM_c10110 LysM domain/M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Peptidase M23.
       0.648
AEJ61306.1
PFAM: ABC transporter; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c10090 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Transporter; manually curated.
       0.492
AEJ61307.1
Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: sta:STHERM_c10100 hypothetical protein; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein.
       0.484
AEJ61304.1
KEGG: sta:STHERM_c10070 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.480
AEJ61305.1
TIGRFAM: RND family efflux transporter, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR000089:IPR006143; KEGG: sta:STHERM_c10080 efflux transporter, RND family, MFP subunit; PFAM: Biotin/lipoyl attachment; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD.
       0.480
AEJ61934.1
uroporphyrin-III C-methyltransferase; PFAM: Porphobilinogen deaminase, dipyromethane cofactor binding domain; Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: porphobilinogen deaminase; uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000860:IPR000878:IPR003754; KEGG: sta:STHERM_c16140 porphyrin biosynthesis protein HemD; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; SPTR: Uroporphyrin-III C-m [...]
  
  
 0.437
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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