Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
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AEJ61349.1KEGG: sta:STHERM_c10500 hypothetical protein; SPTR: Putative uncharacterized protein. (396 aa)    
Predicted Functional Partners:
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
    0.572
AEJ62115.1
Cell division FtsK/SpoIIIE; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR002543:IPR018541:IPR003593; KEGG: sta:STHERM_c17860 DNA translocase FtsK; PFAM: Cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: ATPase, AAA+ type, core; SPTR: Cell division protein FtsK/SpoIIIE; Belongs to the FtsK/SpoIIIE/SftA family.
    
 
 0.559
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
   
 
 0.557
rimM
Ribosome maturation factor rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
  
   0.553
AEJ62173.1
KEGG: sta:STHERM_c18710 cytoskeletal protein; SPTR: Putative uncharacterized protein.
 
 
 
 0.551
rpsP
PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16; COGs: COG0228 Ribosomal protein S16; HAMAP: Ribosomal protein S16; InterPro IPR000307; KEGG: sta:STHERM_c10530 30S ribosomal protein S16; PFAM: Ribosomal protein S16; SPTR: 30S ribosomal protein S16; TIGRFAM: Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
       0.538
AEJ61359.1
UPF0102 protein yraN; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: TIGR00252 family protein; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; HAMAP: Uncharacterised protein family UPF0102; InterPro IPR003509; KEGG: sta:STHERM_c10610 hypothetical protein; PFAM: Uncharacterised protein family UPF0102; SPTR: UPF0102 protein SpithDRAFT_1943.
  
    0.536
AEJ61357.1
Type III secretion exporter; PFAM: FlhB HrpN YscU SpaS Family; COGs: COG1377 Flagellar biosynthesis pathway component FlhB; InterPro IPR006135; KEGG: sta:STHERM_c10590 hypothetical protein; PFAM: Type III secretion exporter; SPTR: Type III secretion exporter.
       0.534
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
       0.533
trmD
tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
       0.527
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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