STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61359.1UPF0102 protein yraN; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: TIGR00252 family protein; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; HAMAP: Uncharacterised protein family UPF0102; InterPro IPR003509; KEGG: sta:STHERM_c10610 hypothetical protein; PFAM: Uncharacterised protein family UPF0102; SPTR: UPF0102 protein SpithDRAFT_1943. (127 aa)    
Predicted Functional Partners:
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
   0.820
AEJ61358.1
Metal dependent phosphohydrolase; PFAM: HD domain; COGs: COG2206 HD-GYP domain; InterPro IPR006674:IPR003607; KEGG: sta:STHERM_c10600 HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase.
       0.808
rimM
Ribosome maturation factor rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
       0.797
trmD
tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
       0.797
AEJ61352.1
UPF0109 protein; PFAM: KH domain; COGs: COG1837 RNA-binding protein (contains KH domain); HAMAP: Uncharacterised protein family UPF0109, bacterial; InterPro IPR018111:IPR020627; KEGG: sta:STHERM_c10540 nucleic acid binding protein, containing KH domain; SPTR: Nucleic acid binding protein, containing KH domain; Belongs to the UPF0109 family.
       0.796
AEJ61357.1
Type III secretion exporter; PFAM: FlhB HrpN YscU SpaS Family; COGs: COG1377 Flagellar biosynthesis pathway component FlhB; InterPro IPR006135; KEGG: sta:STHERM_c10590 hypothetical protein; PFAM: Type III secretion exporter; SPTR: Type III secretion exporter.
       0.796
rpsP
PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16; COGs: COG0228 Ribosomal protein S16; HAMAP: Ribosomal protein S16; InterPro IPR000307; KEGG: sta:STHERM_c10530 30S ribosomal protein S16; PFAM: Ribosomal protein S16; SPTR: 30S ribosomal protein S16; TIGRFAM: Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
       0.782
AEJ61356.1
KEGG: sta:STHERM_c10580 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
       0.733
AEJ60828.1
PFAM: Magnesium chelatase, subunit ChlI; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: Mg chelatase-related protein; COGs: COG0606 ATPase with chaperone activity; InterPro IPR004482:IPR003593:IPR000523; KEGG: sta:STHERM_c05260 hypothetical protein; PFAM: Magnesium chelatase, ChlI subunit; SMART: ATPase, AAA+ type, core; SPTR: Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein.
 
  
 0.654
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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