Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (163 aa)    
Predicted Functional Partners:
coaE
Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
  
 0.942
AEJ60483.1
PFAM: Flavoprotein; COGs: COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; InterPro IPR003382; KEGG: sta:STHERM_c02120 pantothenate metabolism flavoprotein; PFAM: Flavoprotein; SPTR: Phosphopantothenoylcysteine decarboxylase.
  
 
 0.915
AEJ61628.1
Methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR016065:IPR004398; KEGG: sta:STHERM_c08060 hypothetical protein; PFAM: Protein of unknown function methylase putative; SPTR: Methyltransferase; TIGRFAM: Conserved hypothetical protein CHP00095.
 
  
 0.852
AEJ61364.1
Na+/Ca+ antiporter, CaCA family; PFAM: Sodium/calcium exchanger protein; TIGRFAM: K+-dependent Na+/Ca+ exchanger related-protein; COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004837:IPR004481; KEGG: sta:STHERM_c10650 K+-dependent Na+/Ca+ exchanger related-protein; PFAM: Sodium/calcium exchanger membrane region; SPTR: Na+/Ca+ antiporter, CaCA family; TIGRFAM: K+-dependent Na+/Ca+ exchanger-like.
       0.794
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
 
   
 0.631
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
 
   
 0.629
AEJ61416.1
Cytidyltransferase-related domain protein; PFAM: FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; COGs: COG0196 FAD synthase; InterPro IPR015864:IPR004821; KEGG: sta:STHERM_c11150 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; SPTR: Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related.
 
   
 0.628
rpmF
PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32; COGs: COG0333 Ribosomal protein L32; HAMAP: Ribosomal protein L32p; InterPro IPR002677; KEGG: ssm:Spirs_1887 ribosomal protein L32; PFAM: Ribosomal protein L32p; SPTR: 50S ribosomal protein L32; TIGRFAM: Ribosomal protein L32p; Belongs to the bacterial ribosomal protein bL32 family.
  
    0.578
AEJ61362.1
KEGG: sta:STHERM_c10640 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.555
rnc
Ribonuclease 3; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
    0.528
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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