| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEJ60483.1 | coaD | Spith_0196 | Spith_1091 | PFAM: Flavoprotein; COGs: COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; InterPro IPR003382; KEGG: sta:STHERM_c02120 pantothenate metabolism flavoprotein; PFAM: Flavoprotein; SPTR: Phosphopantothenoylcysteine decarboxylase. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.914 |
| AEJ61362.1 | AEJ61364.1 | Spith_1090 | Spith_1092 | KEGG: sta:STHERM_c10640 hypothetical protein; SPTR: Putative uncharacterized protein. | Na+/Ca+ antiporter, CaCA family; PFAM: Sodium/calcium exchanger protein; TIGRFAM: K+-dependent Na+/Ca+ exchanger related-protein; COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004837:IPR004481; KEGG: sta:STHERM_c10650 K+-dependent Na+/Ca+ exchanger related-protein; PFAM: Sodium/calcium exchanger membrane region; SPTR: Na+/Ca+ antiporter, CaCA family; TIGRFAM: K+-dependent Na+/Ca+ exchanger-like. | 0.555 |
| AEJ61362.1 | coaD | Spith_1090 | Spith_1091 | KEGG: sta:STHERM_c10640 hypothetical protein; SPTR: Putative uncharacterized protein. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.555 |
| AEJ61364.1 | AEJ61362.1 | Spith_1092 | Spith_1090 | Na+/Ca+ antiporter, CaCA family; PFAM: Sodium/calcium exchanger protein; TIGRFAM: K+-dependent Na+/Ca+ exchanger related-protein; COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004837:IPR004481; KEGG: sta:STHERM_c10650 K+-dependent Na+/Ca+ exchanger related-protein; PFAM: Sodium/calcium exchanger membrane region; SPTR: Na+/Ca+ antiporter, CaCA family; TIGRFAM: K+-dependent Na+/Ca+ exchanger-like. | KEGG: sta:STHERM_c10640 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.555 |
| AEJ61364.1 | acpP | Spith_1092 | Spith_1094 | Na+/Ca+ antiporter, CaCA family; PFAM: Sodium/calcium exchanger protein; TIGRFAM: K+-dependent Na+/Ca+ exchanger related-protein; COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004837:IPR004481; KEGG: sta:STHERM_c10650 K+-dependent Na+/Ca+ exchanger related-protein; PFAM: Sodium/calcium exchanger membrane region; SPTR: Na+/Ca+ antiporter, CaCA family; TIGRFAM: K+-dependent Na+/Ca+ exchanger-like. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.436 |
| AEJ61364.1 | coaD | Spith_1092 | Spith_1091 | Na+/Ca+ antiporter, CaCA family; PFAM: Sodium/calcium exchanger protein; TIGRFAM: K+-dependent Na+/Ca+ exchanger related-protein; COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004837:IPR004481; KEGG: sta:STHERM_c10650 K+-dependent Na+/Ca+ exchanger related-protein; PFAM: Sodium/calcium exchanger membrane region; SPTR: Na+/Ca+ antiporter, CaCA family; TIGRFAM: K+-dependent Na+/Ca+ exchanger-like. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.796 |
| AEJ61364.1 | rpmF | Spith_1092 | Spith_1093 | Na+/Ca+ antiporter, CaCA family; PFAM: Sodium/calcium exchanger protein; TIGRFAM: K+-dependent Na+/Ca+ exchanger related-protein; COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004837:IPR004481; KEGG: sta:STHERM_c10650 K+-dependent Na+/Ca+ exchanger related-protein; PFAM: Sodium/calcium exchanger membrane region; SPTR: Na+/Ca+ antiporter, CaCA family; TIGRFAM: K+-dependent Na+/Ca+ exchanger-like. | PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32; COGs: COG0333 Ribosomal protein L32; HAMAP: Ribosomal protein L32p; InterPro IPR002677; KEGG: ssm:Spirs_1887 ribosomal protein L32; PFAM: Ribosomal protein L32p; SPTR: 50S ribosomal protein L32; TIGRFAM: Ribosomal protein L32p; Belongs to the bacterial ribosomal protein bL32 family. | 0.494 |
| AEJ61416.1 | coaD | Spith_1144 | Spith_1091 | Cytidyltransferase-related domain protein; PFAM: FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; COGs: COG0196 FAD synthase; InterPro IPR015864:IPR004821; KEGG: sta:STHERM_c11150 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; SPTR: Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.635 |
| AEJ61416.1 | coaE | Spith_1144 | Spith_0226 | Cytidyltransferase-related domain protein; PFAM: FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; COGs: COG0196 FAD synthase; InterPro IPR015864:IPR004821; KEGG: sta:STHERM_c11150 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; SPTR: Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.445 |
| AEJ61526.1 | coaD | Spith_1261 | Spith_1091 | Conserved hypothetical protein CHP00255; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: TIGR00255 family protein; COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR013527:IPR013551:IPR005229; KEGG: sta:STHERM_c12240 protein YicC; PFAM: YicC-like, N-terminal; Domain of unknown function DUF1732; SPTR: YicC-like domain-containing protein; TIGRFAM: Conserved hypothetical protein CHP00255. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.609 |
| AEJ61628.1 | coaD | Spith_1364 | Spith_1091 | Methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR016065:IPR004398; KEGG: sta:STHERM_c08060 hypothetical protein; PFAM: Protein of unknown function methylase putative; SPTR: Methyltransferase; TIGRFAM: Conserved hypothetical protein CHP00095. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.821 |
| acpP | AEJ61364.1 | Spith_1094 | Spith_1092 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Na+/Ca+ antiporter, CaCA family; PFAM: Sodium/calcium exchanger protein; TIGRFAM: K+-dependent Na+/Ca+ exchanger related-protein; COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004837:IPR004481; KEGG: sta:STHERM_c10650 K+-dependent Na+/Ca+ exchanger related-protein; PFAM: Sodium/calcium exchanger membrane region; SPTR: Na+/Ca+ antiporter, CaCA family; TIGRFAM: K+-dependent Na+/Ca+ exchanger-like. | 0.436 |
| acpP | coaD | Spith_1094 | Spith_1091 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.629 |
| acpP | rpmF | Spith_1094 | Spith_1093 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32; COGs: COG0333 Ribosomal protein L32; HAMAP: Ribosomal protein L32p; InterPro IPR002677; KEGG: ssm:Spirs_1887 ribosomal protein L32; PFAM: Ribosomal protein L32p; SPTR: 50S ribosomal protein L32; TIGRFAM: Ribosomal protein L32p; Belongs to the bacterial ribosomal protein bL32 family. | 0.982 |
| coaD | AEJ60483.1 | Spith_1091 | Spith_0196 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | PFAM: Flavoprotein; COGs: COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; InterPro IPR003382; KEGG: sta:STHERM_c02120 pantothenate metabolism flavoprotein; PFAM: Flavoprotein; SPTR: Phosphopantothenoylcysteine decarboxylase. | 0.914 |
| coaD | AEJ61362.1 | Spith_1091 | Spith_1090 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | KEGG: sta:STHERM_c10640 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.555 |
| coaD | AEJ61364.1 | Spith_1091 | Spith_1092 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Na+/Ca+ antiporter, CaCA family; PFAM: Sodium/calcium exchanger protein; TIGRFAM: K+-dependent Na+/Ca+ exchanger related-protein; COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004837:IPR004481; KEGG: sta:STHERM_c10650 K+-dependent Na+/Ca+ exchanger related-protein; PFAM: Sodium/calcium exchanger membrane region; SPTR: Na+/Ca+ antiporter, CaCA family; TIGRFAM: K+-dependent Na+/Ca+ exchanger-like. | 0.796 |
| coaD | AEJ61416.1 | Spith_1091 | Spith_1144 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Cytidyltransferase-related domain protein; PFAM: FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; COGs: COG0196 FAD synthase; InterPro IPR015864:IPR004821; KEGG: sta:STHERM_c11150 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; SPTR: Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related. | 0.635 |
| coaD | AEJ61526.1 | Spith_1091 | Spith_1261 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Conserved hypothetical protein CHP00255; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: TIGR00255 family protein; COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR013527:IPR013551:IPR005229; KEGG: sta:STHERM_c12240 protein YicC; PFAM: YicC-like, N-terminal; Domain of unknown function DUF1732; SPTR: YicC-like domain-containing protein; TIGRFAM: Conserved hypothetical protein CHP00255. | 0.609 |
| coaD | AEJ61628.1 | Spith_1091 | Spith_1364 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR016065:IPR004398; KEGG: sta:STHERM_c08060 hypothetical protein; PFAM: Protein of unknown function methylase putative; SPTR: Methyltransferase; TIGRFAM: Conserved hypothetical protein CHP00095. | 0.821 |