STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61371.1Histidine triad (HIT) protein; PFAM: HIT domain; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: sta:STHERM_c10710 hypothetical protein; PFAM: Histidine triad (HIT) protein; SPTR: Putative uncharacterized protein. (167 aa)    
Predicted Functional Partners:
AEJ61937.1
Sulfate adenylyltransferase, large subunit; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Adenylylsulphate kinase; TIGRFAM: sulfate adenylyltransferase, large subunit; COGs: COG2895 GTPase - Sulfate adenylate transferase subunit 1; InterPro IPR011779:IPR000795:IPR004161; KEGG: sta:STHERM_c16170 sulfate adenylyltransferase large subunit; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; SPTR: Sulfate adenylyltransferase, large subunit; TIGRFAM: Sulphate adenylyltransferase, large subunit.
    
  0.901
AEJ61938.1
PFAM: Phosphoadenosine phosphosulfate reductase family; COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR002500; KEGG: sta:STHERM_c16180 phosphoadenosine phosphosulfate reductase; PFAM: Phosphoadenosine phosphosulphate reductase; SPTR: Sulfate adenylyltransferase subunit 2.
    
  0.901
AEJ61372.1
Hypothetical protein; PFAM: SPFH domain / Band 7 family; KEGG: sta:STHERM_c10720 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.795
AEJ61373.1
PFAM: haloacid dehalogenase-like hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: sta:STHERM_c10730 hypothetical protein; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Haloacid dehalogenase domain protein hydrolase.
       0.787
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
   
   0.659
map-2
Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
   
   0.587
AEJ61374.1
KEGG: sta:STHERM_c10740 hypothetical protein; SPTR: Transport system permease protein.
       0.559
AEJ61376.1
Protein of unknown function UPF0153; PFAM: Uncharacterised protein family (UPF0153); InterPro IPR005358; KEGG: sta:STHERM_c10760 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: Putative uncharacterized protein.
   
   0.522
AEJ61379.1
OmpA/MotB domain protein; PFAM: OmpA family; COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: sta:STHERM_c10790 OmpA family protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; SPTR: OmpA/MotB domain protein.
   
   0.479
AEJ61377.1
Hypothetical protein; PFAM: Metallo-beta-lactamase superfamily; COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; KEGG: sta:STHERM_c10770 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.448
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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