STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEJ61372.1Hypothetical protein; PFAM: SPFH domain / Band 7 family; KEGG: sta:STHERM_c10720 hypothetical protein; SPTR: Putative uncharacterized protein. (270 aa)    
Predicted Functional Partners:
AEJ61373.1
PFAM: haloacid dehalogenase-like hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: sta:STHERM_c10730 hypothetical protein; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Haloacid dehalogenase domain protein hydrolase.
   
   0.805
AEJ61371.1
Histidine triad (HIT) protein; PFAM: HIT domain; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: sta:STHERM_c10710 hypothetical protein; PFAM: Histidine triad (HIT) protein; SPTR: Putative uncharacterized protein.
       0.787
AEJ61895.1
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
  
  
 0.691
map-2
Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
       0.571
AEJ61374.1
KEGG: sta:STHERM_c10740 hypothetical protein; SPTR: Transport system permease protein.
       0.563
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
  
 0.541
AEJ61379.1
OmpA/MotB domain protein; PFAM: OmpA family; COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: sta:STHERM_c10790 OmpA family protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; SPTR: OmpA/MotB domain protein.
  
   0.486
AEJ62195.1
Phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: Prephenate dehydratase; ACT domain; DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR001086:IPR002912:IPR006268; KEGG: sta:STHERM_c18910 hypothetical protein; PFAM: DAHP synthetase I/KDSA; Prephenate dehydratase; Amino acid-binding ACT; SPTR: Phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2.
     
 0.459
AEJ61376.1
Protein of unknown function UPF0153; PFAM: Uncharacterised protein family (UPF0153); InterPro IPR005358; KEGG: sta:STHERM_c10760 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: Putative uncharacterized protein.
       0.447
AEJ61377.1
Hypothetical protein; PFAM: Metallo-beta-lactamase superfamily; COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; KEGG: sta:STHERM_c10770 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.447
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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