STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61377.1Hypothetical protein; PFAM: Metallo-beta-lactamase superfamily; COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; KEGG: sta:STHERM_c10770 hypothetical protein; SPTR: Putative uncharacterized protein. (314 aa)    
Predicted Functional Partners:
AEJ61379.1
OmpA/MotB domain protein; PFAM: OmpA family; COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: sta:STHERM_c10790 OmpA family protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; SPTR: OmpA/MotB domain protein.
 
     0.840
AEJ61376.1
Protein of unknown function UPF0153; PFAM: Uncharacterised protein family (UPF0153); InterPro IPR005358; KEGG: sta:STHERM_c10760 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: Putative uncharacterized protein.
       0.811
AEJ61378.1
KEGG: sta:STHERM_c10780 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ61394.1
Adenylate/guanylate cyclase with Chase sensor; PFAM: Adenylate and Guanylate cyclase catalytic domain; CHASE2 domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR007890:IPR001054; KEGG: sta:STHERM_c10940 hypothetical protein; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase with Chase sensor.
 
     0.766
AEJ60381.1
Adenylate/guanylate cyclase with TPR repeats; PFAM: Adenylate and Guanylate cyclase catalytic domain; HAMP domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR003660:IPR001054:IPR013105; KEGG: sta:STHERM_c01070 adenylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; HAMP linker domain; Tetratricopeptide TPR2; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; HAMP linker domain; SPTR: Adenylate/guanylate cyclase with integral membrane sensor.
 
     0.737
AEJ62073.1
PFAM: Adenylate and Guanylate cyclase catalytic domain; 7TM diverse intracellular signalling; 7TMR-DISM extracellular 2; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054; KEGG: sta:STHERM_c17430 adenylate cyclase / guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase; manually curated.
 
     0.736
AEJ62178.1
Diverse 7TM receptor transmembrane region; PFAM: 7TM diverse intracellular signalling; InterPro IPR011623; KEGG: sta:STHERM_c18750 hypothetical protein; PFAM: Diverse 7TM receptor, transmembrane region; SPTR: Diverse 7TM receptor transmembrane region.
 
     0.727
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
  
    0.703
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
    0.691
AEJ61517.1
Adenylate/guanylate cyclase with integral membrane sensor; PFAM: Adenylate and Guanylate cyclase catalytic domain; HAMP domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR003660:IPR001054; KEGG: sta:STHERM_c12100 adenylate/guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; HAMP linker domain; SMART: HAMP linker domain; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase with integral membrane sensor.
 
     0.663
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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