STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61385.1PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family; COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: sta:STHERM_c10850 hypothetical protein; PFAM: Cell shape determining protein MreB/Mrl; SPTR: Rod shape-determining protein MreB; TIGRFAM: Cell shape determining protein MreB/Mrl. (343 aa)    
Predicted Functional Partners:
AEJ61386.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.994
AEJ61388.1
Penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460:IPR017790; KEGG: sta:STHERM_c10880 penicillin-binding protein; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; SPTR: Penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2.
 
 
 
 0.969
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 
 0.962
AEJ62425.1
Transcriptional regulator, XRE family; COGs: COG1426 conserved hypothetical protein; KEGG: sta:STHERM_c21240 transcriptional regulator, XRE family; SPTR: Putative uncharacterized protein.
 
 
 0.885
AEJ61390.1
Radical SAM domain protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2344); Radical SAM superfamily; TIGRFAM: radical SAM-linked protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197:IPR018768:IPR006638; KEGG: sta:STHERM_c10900 hypothetical protein; PFAM: Radical SAM; Protein of unknown function DUF2344; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein.
       0.814
AEJ61384.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR011717:IPR001440:IPR013105:IPR019734; KEGG: sta:STHERM_c10840 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; Tetratricopeptide TPR-4; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
       0.773
AEJ61387.1
TIGRFAM: rod shape-determining protein MreD; InterPro IPR007227; KEGG: sta:STHERM_c10870 hypothetical protein; SPTR: Rod shape-determining protein MreD; TIGRFAM: Cell shape-determining protein MreD.
       0.773
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.742
AEJ61195.1
PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182:IPR013437; KEGG: sta:STHERM_c08960 hypothetical protein; PFAM: Cell cycle protein; SPTR: Cell division protein FtsW; TIGRFAM: Cell division protein FtsW; Belongs to the SEDS family.
 
 
 0.680
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
    
 
 0.635
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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