STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61388.1Penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460:IPR017790; KEGG: sta:STHERM_c10880 penicillin-binding protein; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; SPTR: Penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2. (619 aa)    
Predicted Functional Partners:
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 0.991
AEJ61386.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.971
AEJ61385.1
PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family; COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: sta:STHERM_c10850 hypothetical protein; PFAM: Cell shape determining protein MreB/Mrl; SPTR: Rod shape-determining protein MreB; TIGRFAM: Cell shape determining protein MreB/Mrl.
 
 
 
 0.969
AEJ61195.1
PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182:IPR013437; KEGG: sta:STHERM_c08960 hypothetical protein; PFAM: Cell cycle protein; SPTR: Cell division protein FtsW; TIGRFAM: Cell division protein FtsW; Belongs to the SEDS family.
 
 0.938
AEJ61683.1
PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543:IPR005311:IPR001460; KEGG: sta:STHERM_c07450 penicillin-binding protein; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA; SMART: PASTA; SPTR: Peptidoglycan glycosyltransferase.
  
  
0.927
AEJ61384.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR011717:IPR001440:IPR013105:IPR019734; KEGG: sta:STHERM_c10840 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; Tetratricopeptide TPR-4; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
    0.824
AEJ61390.1
Radical SAM domain protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2344); Radical SAM superfamily; TIGRFAM: radical SAM-linked protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197:IPR018768:IPR006638; KEGG: sta:STHERM_c10900 hypothetical protein; PFAM: Radical SAM; Protein of unknown function DUF2344; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein.
       0.811
AEJ61705.1
Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460:IPR011816; KEGG: sta:STHERM_c07150 penicillin-binding protein; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; SPTR: Penicillin-binding protein, 1A family; TIGRFAM: Penicillin-binding protein 1A.
 
 
 
 0.777
AEJ61387.1
TIGRFAM: rod shape-determining protein MreD; InterPro IPR007227; KEGG: sta:STHERM_c10870 hypothetical protein; SPTR: Rod shape-determining protein MreD; TIGRFAM: Cell shape-determining protein MreD.
       0.773
AEJ61196.1
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
 
 
 0.762
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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