STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61444.1PFAM: Dinitrogenase iron-molybdenum cofactor; COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: dly:Dehly_0472 dinitrogenase iron-molybdenum cofactor biosynthesis protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; SPTR: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; manually curated. (114 aa)    
Predicted Functional Partners:
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
  
     0.674
AEJ61446.1
PFAM: 4Fe-4S binding domain; InterPro IPR001450; KEGG: ckn:Calkro_0758 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein.
 
   
 0.653
AEJ61443.1
Protein of unknown function DUF318, transmembrane; PFAM: Predicted permease; COGs: COG0701 permease; InterPro IPR005524; KEGG: sta:STHERM_c11410 transporter; PFAM: Protein of unknown function DUF318, transmembrane; SPTR: Permease.
 
    0.624
AEJ61445.1
Hypothetical protein; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; KEGG: tma:TM1174 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.598
AEJ61471.1
KEGG: sta:STHERM_c11660 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.497
AEJ61058.1
ABC-type transporter, integral membrane subunit; PFAM: Cobalt transport protein; InterPro IPR003339; KEGG: sta:STHERM_c14490 hypothetical protein; PFAM: Cobalt transport protein; SPTR: Cobalt transport protein.
  
     0.476
AEJ61442.1
TIGRFAM: small redox-active disulfide protein 2; InterPro IPR005243; KEGG: sta:STHERM_c11400 redox-active disulfide protein 2; SPTR: Redox-active disulfide protein 2; TIGRFAM: Redox-active disulphide protein 2.
       0.437
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
     
 0.434
AEJ60987.1
Hypothetical protein; PFAM: Metallo-beta-lactamase superfamily; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: sta:STHERM_c15130 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
 
     0.402
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.