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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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[Homology]
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AEJ61445.1Hypothetical protein; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; KEGG: tma:TM1174 hypothetical protein; SPTR: Putative uncharacterized protein. (117 aa)    
Predicted Functional Partners:
AEJ61446.1
PFAM: 4Fe-4S binding domain; InterPro IPR001450; KEGG: ckn:Calkro_0758 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein.
 
   
 0.924
AEJ61012.1
PFAM: SirA-like protein; InterPro IPR001455; KEGG: tnp:Tnap_1770 SirA family protein; PFAM: SirA-like; SPTR: SirA-like domain-containing protein; Belongs to the sulfur carrier protein TusA family.
 
   
 0.706
AEJ61010.1
PFAM: DsrE/DsrF-like family; TIGRFAM: sulfur relay protein TusD/DsrE; COGs: COG1553 conserved hypothetical protein involved in intracellular sulfur reduction; InterPro IPR003787; KEGG: tna:CTN_1597 DsrE family protein; PFAM: Sulphur relay, DsrE-like protein; SPTR: DsrE family protein.
  
     0.697
AEJ61011.1
PFAM: YeeE/YedE family (DUF395); InterPro IPR007272; KEGG: tle:Tlet_1313 protein of unknown function DUF395 YeeE/YedE; PFAM: Protein of unknown function DUF395, YeeE/YedE; SPTR: Putative uncharacterized protein.
  
   
 0.615
AEJ61798.1
PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain; COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR001088; KEGG: sta:STHERM_c13990 alpha-glucosidase; PFAM: Glycoside hydrolase, family 4; SPTR: Glycoside hydrolase family 4.
  
     0.609
AEJ61444.1
PFAM: Dinitrogenase iron-molybdenum cofactor; COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: dly:Dehly_0472 dinitrogenase iron-molybdenum cofactor biosynthesis protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; SPTR: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; manually curated.
       0.598
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
  
  
 0.495
AEJ60762.1
PFAM: Bacterial extracellular solute-binding protein; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: dtu:Dtur_1732 extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Carbohydrate ABC transporter substrate-binding protein, CUT1 family.
  
     0.459
AEJ61447.1
PFAM: C4-dicarboxylate transporter/malic acid transport protein; TIGRFAM: C4-dicarboxylate transporter/malic acid transport protein; COGs: COG1275 Tellurite resistance protein and related permease; InterPro IPR004695; KEGG: mfe:Mefer_1360 C4-dicarboxylate transporter/malic acid transport protein; PFAM: C4-dicarboxylate transporter/malic acid transport protein; SPTR: C4-dicarboxylate transporter/malic acid transport protein.
       0.459
AEJ62362.1
PFAM: Glycosyl hydrolase family 12; InterPro IPR002594; KEGG: sta:STHERM_c20650 glycosyl hydrolase family 12, linker, domain X; PFAM: Glycoside hydrolase, family 12; SPTR: Glycoside hydrolase family 12; Belongs to the glycosyl hydrolase 12 (cellulase H) family.
  
     0.452
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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