Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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AEJ61446.1PFAM: 4Fe-4S binding domain; InterPro IPR001450; KEGG: ckn:Calkro_0758 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein. (68 aa)    
Predicted Functional Partners:
AEJ61445.1
Hypothetical protein; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; KEGG: tma:TM1174 hypothetical protein; SPTR: Putative uncharacterized protein.
 
   
 0.924
AEJ61770.1
Hydrogenase, Fe-only; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR019574:IPR001450:IPR004108:IPR 003149:IPR013352; KEGG: sta:STHERM_c13740 hypothetical protein; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S ferredoxin, iron-sulp [...]
   
 
 0.728
AEJ61444.1
PFAM: Dinitrogenase iron-molybdenum cofactor; COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: dly:Dehly_0472 dinitrogenase iron-molybdenum cofactor biosynthesis protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; SPTR: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; manually curated.
 
   
 0.647
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
     
 0.632
AEJ61447.1
PFAM: C4-dicarboxylate transporter/malic acid transport protein; TIGRFAM: C4-dicarboxylate transporter/malic acid transport protein; COGs: COG1275 Tellurite resistance protein and related permease; InterPro IPR004695; KEGG: mfe:Mefer_1360 C4-dicarboxylate transporter/malic acid transport protein; PFAM: C4-dicarboxylate transporter/malic acid transport protein; SPTR: C4-dicarboxylate transporter/malic acid transport protein.
       0.493
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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