Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61469.1KEGG: sta:STHERM_c11640 hypothetical protein; SPTR: Putative uncharacterized protein. (314 aa)    
Predicted Functional Partners:
AEJ61470.1
Type IV pilus assembly PilZ; PFAM: PilZ domain; InterPro IPR009875; KEGG: sta:STHERM_c11650 hypothetical protein; PFAM: Type IV pilus assembly PilZ; SPTR: Type IV pilus assembly PilZ.
       0.806
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
       0.626
AEJ61471.1
KEGG: sta:STHERM_c11660 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.534
AEJ61472.1
PFAM: Radical SAM superfamily; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197:IPR006638; KEGG: sta:STHERM_c11670 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein.
       0.521
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
       0.509
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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