STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61478.1PFAM: N-6 DNA Methylase; HsdM N-terminal domain; COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356; KEGG: cyj:Cyan7822_0692 adenine-specific DNA-methyltransferase; PFAM: DNA methylase, adenine-specific; SPTR: Site-specific DNA-methyltransferase (Adenine-specific). (332 aa)    
Predicted Functional Partners:
AEJ61484.1
PFAM: Domain of unknown function (DUF3387); COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; KEGG: mrb:Mrub_2450 type I site-specific deoxyribonuclease HsdR family; SPTR: Type I site-specific deoxyribonuclease HsdR family.
 
 
 0.996
AEJ61482.1
PFAM: Type I restriction modification DNA specificity domain; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: tte:TTE1545 restriction endonuclease S subunits; PFAM: Restriction endonuclease, type I, S subunit, EcoBI; SPTR: Restriction modification system DNA specificity domain.
 
 
 0.986
AEJ61480.1
PFAM: N-6 DNA Methylase; HsdM N-terminal domain; COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356; KEGG: sin:YN1551_3201 N-6 DNA methylase; PFAM: DNA methylase, adenine-specific; SPTR: N-6 DNA methylase.
 
 
0.977
AEJ61479.1
PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit; COGs: COG4096 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR007409:IPR006935:IPR001650:IPR014001; KEGG: cpo:COPRO5265_1439 type I restriction-modification system, R subunit; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like heli [...]
 
 
 0.943
AEJ61483.1
PFAM: Protein of unknown function (DUF3644); KEGG: cte:CT1443 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.817
AEJ61477.1
KEGG: tai:Taci_1496 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.778
AEJ61481.1
PFAM: PIN domain; InterPro IPR002716; PFAM: PilT protein, N-terminal; SPTR: PilT protein domain protein.
       0.746
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]
    
 
 0.488
AEJ61658.1
PFAM: FlaG protein; InterPro IPR005186; KEGG: sta:STHERM_c07720 hypothetical protein; PFAM: Flagellar protein FlaG protein; SPTR: Flagellar protein FlaG protein.
    
   0.454
AEJ60608.1
PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA); COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: sta:STHERM_c03370 fibronectin-binding protein; PFAM: Protein of unknown function DUF814; Fibronectin-binding A, N-terminal; SPTR: Putative uncharacterized protein.
  
    0.444
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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