STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61488.1PFAM: Aldo/keto reductase family; COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: sta:STHERM_c11760 aldo/keto reductase; PFAM: Aldo/keto reductase; SPTR: Aldo/keto reductase. (331 aa)    
Predicted Functional Partners:
AEJ61487.1
PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-type transcriptional regulator N-terminus; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR009594:IPR000005:IPR018060; KEGG: sta:STHERM_c11750 transcriptional regulator, AraC family; PFAM: AraC-type transcriptional regulator, N-terminal; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family.
 
     0.743
AEJ61489.1
PFAM: Flavin reductase like domain; COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: sta:STHERM_c11810 hypothetical protein; PFAM: Flavin reductase-like, FMN-binding; SPTR: Flavin reductase domain protein FMN-binding.
       0.612
AEJ61486.1
KEGG: sta:STHERM_c11740 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.426
AEJ61005.1
PFAM: Cytochrome b5-like Heme/Steroid binding domain; InterPro IPR001199; KEGG: sta:STHERM_c14910 soluble cytochrome b558; PFAM: Cytochrome b5; SPTR: Cytochrome b5.
   
   0.413
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.