STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61503.1PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845; KEGG: sta:STHERM_c11950 hypothetical protein; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; SPTR: Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I. (582 aa)    
Predicted Functional Partners:
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
 
 
 0.949
AEJ61674.1
PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase; COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR005835:IPR001451; KEGG: sta:STHERM_c07550 glucose-1-phosphate adenylyltransferase; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide repeat; SPTR: Glucose-1-phosphate adenylyltransferase.
  
 
 0.932
AEJ61099.1
PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR005946:IPR000836; KEGG: sta:STHERM_c13320 hypothetical protein; PFAM: Phosphoribosyltransferase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase.
  
 0.926
AEJ61063.1
PFAM: Carbohydrate phosphorylase; TIGRFAM: alpha-glucan phosphorylases; COGs: COG0058 Glucan phosphorylase; InterPro IPR011834:IPR000811; KEGG: sta:STHERM_c14440 hypothetical protein; PFAM: Glycosyl transferase, family 35; SPTR: Phosphorylase; TIGRFAM: Alpha-glucan phosphorylase.
  
 
 0.923
AEJ60376.1
PFAM: Nucleotidyl transferase; COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR005835; KEGG: sta:STHERM_c01020 hypothetical protein; PFAM: Nucleotidyl transferase; SPTR: UDP-glucose pyrophosphorylase.
    
 0.917
AEJ60409.1
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.917
pgi
PFAM: Phosphoglucose isomerase; COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: sta:STHERM_c20070 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.917
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.913
AEJ60931.1
PFAM: Glucokinase; TIGRFAM: glucokinase, proteobacterial type; COGs: COG0837 Glucokinase; InterPro IPR003836; KEGG: sta:STHERM_c06370 glucokinase; PFAM: Glucokinase; SPTR: Glucokinase.
     
 0.912
rbsK
PfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 
 0.906
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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