STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
atpAV-type ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (591 aa)    
Predicted Functional Partners:
AEJ61510.1
Hypothetical protein; PFAM: ATP synthase subunit C; KEGG: sta:STHERM_c12030 hypothetical protein; SPTR: V-type ATP synthase subunit K.
 
 0.999
AEJ61511.1
PFAM: V-type ATPase 116kDa subunit family; COGs: COG1269 H+-ATPase subunit I; InterPro IPR002490; KEGG: sta:STHERM_c12040 hypothetical protein; PFAM: ATPase, V0/A0 complex, 116kDa subunit; SPTR: V-type ATPase 116 kDa subunit.
 
 0.999
atpD
V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 0.999
atpB
V-type ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.
 
0.999
AEJ61516.1
V-type ATPase subunit E; PFAM: HrpE protein; KEGG: sta:STHERM_c12090 V-type ATPase subunit E; SPTR: V-type ATP synthase subunit E.
 
 0.999
AEJ61515.1
PFAM: Protein of unknown function (DUF2764); KEGG: sta:STHERM_c12080 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.902
AEJ60647.1
PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 1; COGs: COG1085 Galactose-1-phosphate uridylyltransferase; InterPro IPR001937:IPR005849:IPR005850; KEGG: sta:STHERM_c03970 galactose-1-phosphate uridylyltransferase; PFAM: Galactose-1-phosphate uridyl transferase, N-terminal; Galactose-1-phosphate uridyl transferase, C-terminal; SPTR: Galactose-1-phosphate uridylyltransferase; TIGRFAM: Galactose-1-phosphate uridyl transferase, class I.
 
      0.781
AEJ62144.1
Isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type; COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR001804:IPR004439; KEGG: sta:STHERM_c18430 isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; SPTR: Isocitrate dehydrogenase (NADP); TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic.
   
  
 0.659
rnfB
Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
  
 
 0.574
AEJ61508.1
Hypothetical protein; InterPro IPR019734; KEGG: sta:STHERM_c12010 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.572
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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