Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61530.1PFAM: Major Facilitator Superfamily; COGs: COG0738 Fucose permease; InterPro IPR011701; KEGG: sta:STHERM_c12280 hypothetical protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1. (397 aa)    
Predicted Functional Partners:
AEJ61531.1
PFAM: Alkaline phosphatase; COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: sta:STHERM_c12290 alkaline phosphatase; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase.
 
     0.598
AEJ61528.1
KEGG: sta:STHERM_c12260 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.543
AEJ61529.1
SMC domain protein; COGs: COG4637 ATPase; InterPro IPR003395; KEGG: sta:STHERM_c12270 hypothetical protein; PFAM: RecF/RecN/SMC protein, N-terminal; SPTR: SMC domain protein.
       0.543
cmk-2
PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase, putative; COGs: COG1102 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR000623:IPR011892; KEGG: sta:STHERM_c12230 cytidylate kinase; PFAM: Shikimate kinase; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase, putative.
       0.490
AEJ61526.1
Conserved hypothetical protein CHP00255; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: TIGR00255 family protein; COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR013527:IPR013551:IPR005229; KEGG: sta:STHERM_c12240 protein YicC; PFAM: YicC-like, N-terminal; Domain of unknown function DUF1732; SPTR: YicC-like domain-containing protein; TIGRFAM: Conserved hypothetical protein CHP00255.
       0.490
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
       0.490
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
     
 0.431
AEJ61532.1
PFAM: YibE/F-like protein; COGs: COG5438 multitransmembrane protein; InterPro IPR012507; KEGG: sta:STHERM_c12300 multitransmembrane protein-like protein; PFAM: YibE/F-like; SPTR: YibE/F family protein.
       0.428
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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