STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61539.1Fe-S cluster domain protein; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Putative Fe-S cluster; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR001450:IPR007202; KEGG: sta:STHERM_c12360 hypothetical protein; PFAM: Putative Fe-S cluster; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Fe-S cluster domain protein. (574 aa)    
Predicted Functional Partners:
AEJ61540.1
Hypothetical protein; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; KEGG: sta:STHERM_c12370 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 
 0.967
AEJ61537.1
Hypothetical protein; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; KEGG: sta:STHERM_c12340 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 
 0.957
AEJ61538.1
PFAM: Stage II sporulation protein E (SpoIIE); InterPro IPR010822; KEGG: sta:STHERM_c12350 hypothetical protein; PFAM: Sporulation stage II, protein E C-terminal; SPTR: Putative uncharacterized protein.
 
     0.955
AEJ61771.1
Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538:IPR019554:IPR019575:IPR001450; KEGG: sta:STHERM_c13750 hypothetical protein; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4 [...]
 
 
 
 0.873
AEJ61536.1
PFAM: Iron only hydrogenase large subunit, C-terminal domain; 4Fe-4S binding domain; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR001450:IPR004108; KEGG: sta:STHERM_c12330 hypothetical protein; PFAM: Iron hydrogenase, large subunit, C-terminal; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Hydrogenase large subunit domain protein.
 
    
0.851
AEJ60919.1
PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538:IPR019554:IPR019575; KEGG: sta:STHERM_c06250 NADH-quinone oxidoreductase subunit 1; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: NADH dehydrogenase (Quinone).
   
 
 0.815
AEJ61772.1
KEGG: sta:STHERM_c13760 hypothetical protein; SPTR: NADP-reducing hydrogenase, subunit B.
 
 
 
 0.714
AEJ60767.1
PFAM: Radical SAM superfamily; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydE; COGs: COG0502 Biotin synthase; InterPro IPR006638:IPR007197; KEGG: sta:STHERM_c17990 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein.
 
  
 0.671
AEJ60769.1
Small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: hydrogenase maturation GTPase HydF; small GTP-binding protein domain; COGs: COG1160 GTPase; InterPro IPR005225:IPR002917; KEGG: sta:STHERM_c17970 hypothetical protein; PFAM: GTP-binding protein, HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: Small GTP-binding protein.
 
   
 0.667
AEJ60845.1
Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterPro IPR000014:IPR003661:IPR003594:IPR013656; KEGG: sta:STHERM_c05430 sensory transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; SMART: ATP-binding region, ATPase-like; Signal transduction histidine [...]
 
      0.649
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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