STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61544.1Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: sta:STHERM_c12410 lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein. (424 aa)    
Predicted Functional Partners:
AEJ61546.1
Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: sta:STHERM_c12430 lipoprotein releasing system, permease; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein.
 
  
0.985
AEJ61545.1
PFAM: ABC transporter; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: sta:STHERM_c12420 lipoprotein-releasing system ATP-binding protein LolD; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
 
 0.984
AEJ62539.1
Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: sta:STHERM_c22440 permease of an ABC transporter system; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein.
  
  
 
0.929
AEJ61549.1
PFAM: PEGA domain; InterPro IPR013229; KEGG: sta:STHERM_c12460 hypothetical protein; PFAM: PEGA; SPTR: PEGA domain protein.
 
     0.816
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
     
 0.812
prfB
Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
       0.793
AEJ61547.1
KEGG: sta:STHERM_c12440 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ61427.1
PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein; COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184:IPR016474; KEGG: sta:STHERM_c11250 surface antigen; PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Outer membrane protein assembly complex, YaeT protein; TIGRFAM: Outer membrane assembly protein, YaeT.
 
   
 0.676
AEJ61542.1
PFAM: ATP:guanido phosphotransferase, C-terminal catalytic domain; COGs: COG3869 Arginine kinase; InterPro IPR000749; KEGG: sta:STHERM_c12390 hypothetical protein; PFAM: ATP:guanido phosphotransferase; SPTR: ATP:guanido phosphotransferase.
       0.634
AEJ61543.1
PFAM: UvrB/uvrC motif; COGs: COG3880 Uncharacterized protein with conserved CXXC pairs; InterPro IPR001943; KEGG: sta:STHERM_c12400 hypothetical protein; PFAM: UvrB/UvrC protein; SPTR: Putative uncharacterized protein.
       0.632
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.