STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61547.1KEGG: sta:STHERM_c12440 hypothetical protein; SPTR: Putative uncharacterized protein. (354 aa)    
Predicted Functional Partners:
AEJ61544.1
Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: sta:STHERM_c12410 lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein.
       0.773
AEJ61545.1
PFAM: ABC transporter; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: sta:STHERM_c12420 lipoprotein-releasing system ATP-binding protein LolD; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
       0.773
AEJ61546.1
Protein of unknown function DUF214; PFAM: Predicted permease; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: sta:STHERM_c12430 lipoprotein releasing system, permease; PFAM: Protein of unknown function DUF214, permase predicted; SPTR: Putative uncharacterized protein.
       0.773
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
       0.773
AEJ61549.1
PFAM: PEGA domain; InterPro IPR013229; KEGG: sta:STHERM_c12460 hypothetical protein; PFAM: PEGA; SPTR: PEGA domain protein.
       0.752
prfB
Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
       0.752
AEJ61542.1
PFAM: ATP:guanido phosphotransferase, C-terminal catalytic domain; COGs: COG3869 Arginine kinase; InterPro IPR000749; KEGG: sta:STHERM_c12390 hypothetical protein; PFAM: ATP:guanido phosphotransferase; SPTR: ATP:guanido phosphotransferase.
       0.563
AEJ61543.1
PFAM: UvrB/uvrC motif; COGs: COG3880 Uncharacterized protein with conserved CXXC pairs; InterPro IPR001943; KEGG: sta:STHERM_c12400 hypothetical protein; PFAM: UvrB/UvrC protein; SPTR: Putative uncharacterized protein.
       0.563
AEJ61541.1
ATPase AAA-2 domain protein; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; UvrB/uvrC motif; ATPase family associated with various cellular activities (AAA); COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR004176:IPR003959:IPR001943:IPR 013093:IPR019489; KEGG: sta:STHERM_c12380 chaperone ClpB; PFAM: ATPase associated with various cellular activities, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; UvrB/UvrC protein; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATPase AA [...]
       0.535
AEJ61551.1
PFAM: Cellulase (glycosyl hydrolase family 5); InterPro IPR001547; KEGG: sta:STHERM_c12480 cellulase, glycosyl hydrolase family 5; PFAM: Glycoside hydrolase, family 5; SPTR: Mannan endo-1,4-beta-mannosidase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
       0.446
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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