| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEJ60917.1 | AEJ61466.1 | Spith_0637 | Spith_1196 | Malic protein NAD-binding protein; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302; KEGG: sta:STHERM_c06230 hypothetical protein; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; SPTR: Malic protein NAD-binding. | PFAM: Citrate synthase; COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: sta:STHERM_c11610 hypothetical protein; PFAM: Citrate synthase-like; SPTR: Citrate synthase. | 0.889 |
| AEJ60917.1 | AEJ61568.1 | Spith_0637 | Spith_1303 | Malic protein NAD-binding protein; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302; KEGG: sta:STHERM_c06230 hypothetical protein; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; SPTR: Malic protein NAD-binding. | PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR004614; KEGG: sta:STHERM_c08690 phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; SPTR: Phosphotransacetylase; TIGRFAM: Phosphate acetyltransferase. | 0.925 |
| AEJ60917.1 | AEJ61982.1 | Spith_0637 | Spith_1722 | Malic protein NAD-binding protein; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302; KEGG: sta:STHERM_c06230 hypothetical protein; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; SPTR: Malic protein NAD-binding. | PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...] | 0.951 |
| AEJ60917.1 | AEJ62280.1 | Spith_0637 | Spith_2022 | Malic protein NAD-binding protein; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302; KEGG: sta:STHERM_c06230 hypothetical protein; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; SPTR: Malic protein NAD-binding. | Transketolase domain-containing protein; PFAM: Dehydrogenase E1 component; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; Transketolase, C-terminal domain; Biotin-requiring enzyme; Transketolase, pyrimidine binding domain; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterProIPR001017:IPR005475:IPR005476:IPR000089:IPR 013751:IPR013747; KEGG: sta:STHERM_c19760 hypothetical protein; PFAM: Tr [...] | 0.796 |
| AEJ61466.1 | AEJ60917.1 | Spith_1196 | Spith_0637 | PFAM: Citrate synthase; COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: sta:STHERM_c11610 hypothetical protein; PFAM: Citrate synthase-like; SPTR: Citrate synthase. | Malic protein NAD-binding protein; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302; KEGG: sta:STHERM_c06230 hypothetical protein; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; SPTR: Malic protein NAD-binding. | 0.889 |
| AEJ61466.1 | AEJ61568.1 | Spith_1196 | Spith_1303 | PFAM: Citrate synthase; COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: sta:STHERM_c11610 hypothetical protein; PFAM: Citrate synthase-like; SPTR: Citrate synthase. | PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR004614; KEGG: sta:STHERM_c08690 phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; SPTR: Phosphotransacetylase; TIGRFAM: Phosphate acetyltransferase. | 0.931 |
| AEJ61466.1 | AEJ61580.1 | Spith_1196 | Spith_1315 | PFAM: Citrate synthase; COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: sta:STHERM_c11610 hypothetical protein; PFAM: Citrate synthase-like; SPTR: Citrate synthase. | PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR005481:IPR005479:IPR005482:IPR004549; KEGG: sta:STHERM_c08570 pyruvate carboxylase subunit A; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; SPTR: Biotin carboxylase; acetyl-CoA carboxylase [...] | 0.852 |
| AEJ61466.1 | AEJ61611.1 | Spith_1196 | Spith_1347 | PFAM: Citrate synthase; COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: sta:STHERM_c11610 hypothetical protein; PFAM: Citrate synthase-like; SPTR: Citrate synthase. | Catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078; KEGG: sta:STHERM_c08240 hypothetical protein; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding; SPTR: Catalytic domain-containing protein of component of various dehydrogenase complexes. | 0.971 |
| AEJ61466.1 | AEJ61982.1 | Spith_1196 | Spith_1722 | PFAM: Citrate synthase; COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: sta:STHERM_c11610 hypothetical protein; PFAM: Citrate synthase-like; SPTR: Citrate synthase. | PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...] | 0.955 |
| AEJ61466.1 | AEJ62266.1 | Spith_1196 | Spith_2008 | PFAM: Citrate synthase; COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: sta:STHERM_c11610 hypothetical protein; PFAM: Citrate synthase-like; SPTR: Citrate synthase. | Catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078; KEGG: sta:STHERM_c19600 dihydrolipoyllysine-residue acetyltransferase component of pyruvatedehydrogenase complex (E2); PFAM: 2-oxoacid dehydrogenase acyltransfer [...] | 0.971 |
| AEJ61466.1 | AEJ62280.1 | Spith_1196 | Spith_2022 | PFAM: Citrate synthase; COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: sta:STHERM_c11610 hypothetical protein; PFAM: Citrate synthase-like; SPTR: Citrate synthase. | Transketolase domain-containing protein; PFAM: Dehydrogenase E1 component; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; Transketolase, C-terminal domain; Biotin-requiring enzyme; Transketolase, pyrimidine binding domain; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterProIPR001017:IPR005475:IPR005476:IPR000089:IPR 013751:IPR013747; KEGG: sta:STHERM_c19760 hypothetical protein; PFAM: Tr [...] | 0.984 |
| AEJ61466.1 | accA | Spith_1196 | Spith_1313 | PFAM: Citrate synthase; COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: sta:STHERM_c11610 hypothetical protein; PFAM: Citrate synthase-like; SPTR: Citrate synthase. | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.810 |
| AEJ61568.1 | AEJ60917.1 | Spith_1303 | Spith_0637 | PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR004614; KEGG: sta:STHERM_c08690 phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; SPTR: Phosphotransacetylase; TIGRFAM: Phosphate acetyltransferase. | Malic protein NAD-binding protein; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302; KEGG: sta:STHERM_c06230 hypothetical protein; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; SPTR: Malic protein NAD-binding. | 0.925 |
| AEJ61568.1 | AEJ61466.1 | Spith_1303 | Spith_1196 | PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR004614; KEGG: sta:STHERM_c08690 phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; SPTR: Phosphotransacetylase; TIGRFAM: Phosphate acetyltransferase. | PFAM: Citrate synthase; COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: sta:STHERM_c11610 hypothetical protein; PFAM: Citrate synthase-like; SPTR: Citrate synthase. | 0.931 |
| AEJ61568.1 | AEJ61580.1 | Spith_1303 | Spith_1315 | PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR004614; KEGG: sta:STHERM_c08690 phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; SPTR: Phosphotransacetylase; TIGRFAM: Phosphate acetyltransferase. | PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR005481:IPR005479:IPR005482:IPR004549; KEGG: sta:STHERM_c08570 pyruvate carboxylase subunit A; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; SPTR: Biotin carboxylase; acetyl-CoA carboxylase [...] | 0.914 |
| AEJ61568.1 | AEJ61611.1 | Spith_1303 | Spith_1347 | PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR004614; KEGG: sta:STHERM_c08690 phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; SPTR: Phosphotransacetylase; TIGRFAM: Phosphate acetyltransferase. | Catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078; KEGG: sta:STHERM_c08240 hypothetical protein; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding; SPTR: Catalytic domain-containing protein of component of various dehydrogenase complexes. | 0.925 |
| AEJ61568.1 | AEJ61982.1 | Spith_1303 | Spith_1722 | PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR004614; KEGG: sta:STHERM_c08690 phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; SPTR: Phosphotransacetylase; TIGRFAM: Phosphate acetyltransferase. | PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...] | 0.975 |
| AEJ61568.1 | AEJ62266.1 | Spith_1303 | Spith_2008 | PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR004614; KEGG: sta:STHERM_c08690 phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; SPTR: Phosphotransacetylase; TIGRFAM: Phosphate acetyltransferase. | Catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078; KEGG: sta:STHERM_c19600 dihydrolipoyllysine-residue acetyltransferase component of pyruvatedehydrogenase complex (E2); PFAM: 2-oxoacid dehydrogenase acyltransfer [...] | 0.925 |
| AEJ61568.1 | AEJ62280.1 | Spith_1303 | Spith_2022 | PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR004614; KEGG: sta:STHERM_c08690 phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; SPTR: Phosphotransacetylase; TIGRFAM: Phosphate acetyltransferase. | Transketolase domain-containing protein; PFAM: Dehydrogenase E1 component; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; Transketolase, C-terminal domain; Biotin-requiring enzyme; Transketolase, pyrimidine binding domain; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterProIPR001017:IPR005475:IPR005476:IPR000089:IPR 013751:IPR013747; KEGG: sta:STHERM_c19760 hypothetical protein; PFAM: Tr [...] | 0.942 |
| AEJ61568.1 | AEJ62316.1 | Spith_1303 | Spith_2059 | PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR004614; KEGG: sta:STHERM_c08690 phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; SPTR: Phosphotransacetylase; TIGRFAM: Phosphate acetyltransferase. | PFAM: Acylphosphatase; COGs: COG1254 Acylphosphatase; HAMAP: Acylphosphatase; InterPro IPR001792; KEGG: sta:STHERM_c20090 acylphosphatase; PFAM: Acylphosphatase-like; SPTR: Acylphosphatase. | 0.921 |