STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61587.1PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR018060:IPR000005; KEGG: sta:STHERM_c08500 transcriptional regulatory protein; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family. (760 aa)    
Predicted Functional Partners:
AEJ62404.1
PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain; COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR003313:IPR000005:IPR018060; KEGG: sta:STHERM_c21040 transcriptional regulatory protein; PFAM: AraC protein, arabinose-binding/dimerisation; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family.
 
 
 
 0.803
AEJ61585.1
KEGG: sta:STHERM_c08520 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.768
AEJ61586.1
PFAM: Glycosyl hydrolases family 43; InterPro IPR006710; KEGG: sta:STHERM_c08510 hypothetical protein; PFAM: Glycoside hydrolase, family 43; SPTR: Glycoside hydrolase family 43.
       0.768
AEJ61588.1
PFAM: Bacterial extracellular solute-binding protein; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c08490 extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1.
 
   
 0.675
AEJ61487.1
PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-type transcriptional regulator N-terminus; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR009594:IPR000005:IPR018060; KEGG: sta:STHERM_c11750 transcriptional regulator, AraC family; PFAM: AraC-type transcriptional regulator, N-terminal; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family.
 
 
 0.674
AEJ61595.1
Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR010559:IPR003594; KEGG: sta:STHERM_c08410 two-component sensor histidine kinase; PFAM: Signal transduction histidine kinase, internal region; HAMP linker domain; ATP-binding region, ATPase-like; SPTR: Integral membrane sensor signal transduction histidine kinase.
 
   
 0.628
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.579
AEJ61590.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG4209 ABC-type polysaccharide transport system permease component; InterPro IPR000515; KEGG: sta:STHERM_c08470 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 1, CUT1 family.
 
     0.569
AEJ61589.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: sta:STHERM_c08480 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 2, CUT1 family.
 
   
 0.564
AEJ61605.1
Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR003594:IPR010559; KEGG: sta:STHERM_c08300 hypothetical protein; PFAM: Signal transduction histidine kinase, internal region; HAMP linker domain; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; HAMP linker domain; SPTR: Integral membrane sensor signal transduction histidine kinase.
 
   
 0.534
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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