STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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[Homology]
Score
AEJ61595.1Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR010559:IPR003594; KEGG: sta:STHERM_c08410 two-component sensor histidine kinase; PFAM: Signal transduction histidine kinase, internal region; HAMP linker domain; ATP-binding region, ATPase-like; SPTR: Integral membrane sensor signal transduction histidine kinase. (607 aa)    
Predicted Functional Partners:
AEJ61594.1
Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR018060:IPR000005; KEGG: sta:STHERM_c08420 transcriptional regulatory protein; PFAM: Signal transduction response regulator, receiver region; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulato [...]
 
 
 0.989
AEJ61604.1
Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR018060:IPR000005; KEGG: sta:STHERM_c08310 hypothetical protein; PFAM: Signal transduction response regulator, receiver region; Helix-turn-helix, AraC type; SMART: Signal transduction response regulator, receiver region; Helix-turn-helix, AraC domain; SPTR: Two component transcriptional regulator, AraC family.
 
 
 0.967
AEJ62396.1
PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR000005:IPR018060; KEGG: sta:STHERM_c20960 transcriptional regulatory protein; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family.
 
 
 0.952
AEJ61603.1
PFAM: family; TIGRFAM: rhamnose ABC transporter, rhamnose-binding protein; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR013459; KEGG: sta:STHERM_c08320 transporter; SPTR: Rhamnose-binding protein; TIGRFAM: Rhamnose ABC transporter, rhamnose-binding.
  
 
 0.746
rhaA
PFAM: L-rhamnose isomerase (RhaA); TIGRFAM: L-rhamnose isomerase; COGs: COG4806 L-rhamnose isomerase; HAMAP: L-rhamnose isomerase; InterPro IPR009308; KEGG: sta:STHERM_c08380 L-rhamnose isomerase; PFAM: Rhamnose isomerase; SPTR: L-rhamnose isomerase; TIGRFAM: Rhamnose isomerase.
  
    0.730
AEJ61599.1
L-rhamnose mutarotase; Involved in the anomeric conversion of L-rhamnose.
  
    0.724
AEJ61596.1
PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR003660; KEGG: sta:STHERM_c08400 hypothetical protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer.
       0.723
rbsA-2
ABC transporter related protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
  
    0.710
AEJ61598.1
Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain; COGs: COG3347 conserved hypothetical protein; InterPro IPR001303; KEGG: sta:STHERM_c08370 short chain dehydrogenase; PFAM: Class II aldolase/adducin, N-terminal; SPTR: Class II aldolase/adducin family protein.
       0.707
AEJ61600.1
ABC-type transporter, integral membrane subunit; PFAM: Branched-chain amino acid transport system / permease component; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: sta:STHERM_c08350 transporter; PFAM: Bacterial inner-membrane translocator; SPTR: Monosaccharide ABC transporter membrane protein, CUT2 family.
  
    0.706
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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