STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61607.1PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484; KEGG: sta:STHERM_c08280 hypothetical protein; PFAM: Carbohydrate kinase, FGGY, N-terminal; SPTR: Carbohydrate kinase, FGGY. (506 aa)    
Predicted Functional Partners:
AEJ61599.1
L-rhamnose mutarotase; Involved in the anomeric conversion of L-rhamnose.
 
  
 0.949
AEJ61606.1
PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: sta:STHERM_c08290 L-sorbose 1-phosphate reductase; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; SPTR: Alcohol dehydrogenase zinc-binding domain protein.
  
  
 0.802
rhaA
PFAM: L-rhamnose isomerase (RhaA); TIGRFAM: L-rhamnose isomerase; COGs: COG4806 L-rhamnose isomerase; HAMAP: L-rhamnose isomerase; InterPro IPR009308; KEGG: sta:STHERM_c08380 L-rhamnose isomerase; PFAM: Rhamnose isomerase; SPTR: L-rhamnose isomerase; TIGRFAM: Rhamnose isomerase.
  
  
 0.774
AEJ61608.1
Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: sta:STHERM_c08270 hypothetical protein; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR.
  
  
 0.772
AEJ61603.1
PFAM: family; TIGRFAM: rhamnose ABC transporter, rhamnose-binding protein; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR013459; KEGG: sta:STHERM_c08320 transporter; SPTR: Rhamnose-binding protein; TIGRFAM: Rhamnose ABC transporter, rhamnose-binding.
 
  
 0.771
AEJ61610.1
Transketolase central region; PFAM: Dehydrogenase E1 component; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR001017:IPR005475:IPR005476; KEGG: sta:STHERM_c08250 dehydrogenase, fusion; PFAM: Transketolase-like, pyrimidine-binding domain; Dehydrogenase, E1 component; Transketolase, C-terminal; SPTR: Transketolase central region.
       0.762
AEJ61609.1
Hypothetical protein; PFAM: PHP domain; KEGG: sta:STHERM_c08260 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.760
AEJ61605.1
Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR003594:IPR010559; KEGG: sta:STHERM_c08300 hypothetical protein; PFAM: Signal transduction histidine kinase, internal region; HAMP linker domain; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; HAMP linker domain; SPTR: Integral membrane sensor signal transduction histidine kinase.
       0.742
AEJ61604.1
Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR018060:IPR000005; KEGG: sta:STHERM_c08310 hypothetical protein; PFAM: Signal transduction response regulator, receiver region; Helix-turn-helix, AraC type; SMART: Signal transduction response regulator, receiver region; Helix-turn-helix, AraC domain; SPTR: Two component transcriptional regulator, AraC family.
       0.739
AEJ61598.1
Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain; COGs: COG3347 conserved hypothetical protein; InterPro IPR001303; KEGG: sta:STHERM_c08370 short chain dehydrogenase; PFAM: Class II aldolase/adducin, N-terminal; SPTR: Class II aldolase/adducin family protein.
 
   
 0.717
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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