STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61621.1PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: sta:STHERM_c08130 spore coat polysaccharide biosynthesis protein C; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (397 aa)    
Predicted Functional Partners:
AEJ61620.1
PFAM: Polysaccharide biosynthesis protein; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: sta:STHERM_c08150 capsular polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein CapD-like; SPTR: Polysaccharide biosynthesis protein CapD.
 
  
 0.987
AEJ62247.1
N-acetylneuraminic acid synthase domain-containing protein; PFAM: SAF domain; NeuB family; COGs: COG2089 Sialic acid synthase; InterPro IPR013132:IPR013974; KEGG: sta:STHERM_c19430 NeuB family protein; PFAM: N-acetylneuraminic acid synthase, N-terminal; SAF domain; SPTR: N-acetylneuraminic acid synthase domain.
 
  
 0.861
AEJ61622.1
PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674:IPR008274; KEGG: sta:STHERM_c08120 xanthine dehydrogenase, molybdopterin binding subunit; PFAM: Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead; Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding; SPTR: Aldehyde oxidase and xanthine dehydrogenase a/b hammerhead.
       0.811
AEJ61623.1
Hypothetical protein; COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; KEGG: sta:STHERM_c08110 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.811
AEJ61624.1
PFAM: FAD binding domain in molybdopterin dehydrogenase; COGs: COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs; InterPro IPR002346; KEGG: sta:STHERM_c08100 xanthine dehydrogenase subunit, FAD-binding domain-containing protein; PFAM: Molybdopterin dehydrogenase, FAD-binding; SPTR: Molybdopterin dehydrogenase FAD-binding.
  
    0.806
AEJ61260.1
PFAM: Cytidylyltransferase; COGs: COG1861 Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase homolog; InterPro IPR003329; KEGG: sta:STHERM_c09620 polysaccharide biosynthesis protein; PFAM: Acylneuraminate cytidylyltransferase; SPTR: Acylneuraminate cytidylyltransferase.
 
  
 0.792
AEJ61908.1
Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: rha:RHA1_ro08212 NADH-dependent oxidoreductase; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; SPTR: Oxidoreductase domain protein.
 
  
 0.737
AEJ60912.1
Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: sta:STHERM_c06180 oxidoreductase domain-containing protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; SPTR: Oxidoreductase domain protein.
 
  
 0.733
AEJ61888.1
Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR017475:IPR003362; KEGG: tth:TTC0275 undecaprenyl-phosphate galactosephosphotransferase; PFAM: Bacterial sugar transferase; SPTR: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; TIGRFAM: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.
 
  
 0.614
AEJ61619.1
Sporulation domain-containing protein; PFAM: Sporulation related domain; InterPro IPR005132:IPR007730; KEGG: sta:STHERM_c08160 hypothetical protein; PFAM: Sporulation/cell division region, bacteria; Rare lipoprotein A; SPTR: Sporulation domain-containing protein.
  
    0.583
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.