STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61640.1PFAM: NUDIX domain; InterPro IPR000086; KEGG: sta:STHERM_c07930 hypothetical protein; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase. (232 aa)    
Predicted Functional Partners:
nnrD
YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family.
  
 0.821
AEJ61639.1
PFAM: UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: sta:STHERM_c07940 hypothetical protein; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase.
       0.767
AEJ61638.1
PFAM: Putative small multi-drug export protein; COGs: COG2426 membrane protein; InterPro IPR009577; KEGG: sta:STHERM_c07950 small multidrug export protein QacE; PFAM: Putative small multi-drug export; SPTR: Small multi-drug export protein.
       0.756
AEJ61636.1
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: CBS domain; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR000644:IPR002178; KEGG: sta:STHERM_c07970 hypothetical protein; PFAM: Cystathionine beta-synthase, core; Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SMART: Cystathionine beta-synthase, core; SPTR: Putative PTS IIA-like nitrogen-regulatory protein PtsN.
       0.661
AEJ61637.1
PFAM: Citrate transporter; COGs: COG1055 Na+/H+ antiporter NhaD and related arsenite permease; InterPro IPR004680; KEGG: sta:STHERM_c07960 hypothetical protein; PFAM: Divalent ion symporter; SPTR: Possible tyrosine transporter P-protein.
       0.654
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
   
    0.652
AEJ61091.1
ATP-dependent RNA helicase RhlB; PFAM: DEAD/DEAH box helicase; COGs: COG0513 Superfamily II DNA and RNA helicase; KEGG: sta:STHERM_c14160 ATP-dependent RNA helicase RhlB; SPTR: Putative uncharacterized protein.
  
 0.534
AEJ61988.1
PFAM: DbpA RNA binding domain; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR005580; KEGG: sta:STHERM_c16690 hypothetical protein; PFAM: DbpA, RNA-binding; SPTR: DbpA RNA-binding domain protein.
  
 0.534
AEJ61641.1
Hydrolase, TatD family; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR001130:IPR015991; KEGG: sta:STHERM_c07890 hypothetical protein; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote.
  
    0.531
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
     
 0.421
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.