STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AEJ61659.1Flagellar hook-associated 2 domain-containing protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. (671 aa)    
Predicted Functional Partners:
AEJ61223.1
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
 
  
 0.994
AEJ61658.1
PFAM: FlaG protein; InterPro IPR005186; KEGG: sta:STHERM_c07720 hypothetical protein; PFAM: Flagellar protein FlaG protein; SPTR: Flagellar protein FlaG protein.
 
  
 0.991
AEJ61208.1
PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE; COGs: COG1677 Flagellar hook-basal body protein; InterPro IPR001624; KEGG: sta:STHERM_c09090 flagellar hook-basal body complex protein FliE; PFAM: Flagellar hook-basal body complex protein FliE; SPTR: Flagellar hook-basal body complex subunit FliE; TIGRFAM: Flagellar hook-basal body complex protein FliE.
 
  
 0.980
AEJ61668.1
Flagellar hook-associated protein FlgK; PFAM: Flagellin hook IN motif; Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK; COGs: COG1256 Flagellar hook-associated protein; InterPro IPR010810:IPR010930:IPR002371; KEGG: sta:STHERM_c07620 flagellar hook-associated protein; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellin hook, IN motif; SPTR: Flagellar hook-associated protein FlgK; TIGRFAM: Flagellar hook-associated protein, FlgK.
 
  
 0.980
AEJ61209.1
Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
 
  
 0.979
AEJ61221.1
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
 
  
 0.968
AEJ62052.1
MCP methyltransferase, CheR-type; PFAM: CheW-like domain; CheR methyltransferase, SAM binding domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545:IPR000780; KEGG: sta:STHERM_c17220 chemotaxis protein CheW; PFAM: MCP methyltransferase, CheR-type; CheW-like protein; SMART: CheW-like protein; MCP methyltransferase, CheR-type; SPTR: MCP methyltransferase, CheR-type.
 
  
 0.966
AEJ60509.1
PFAM: Flagellar protein FliS; TIGRFAM: flagellar biosynthetic protein FliS; COGs: COG1516 Flagellin-specific chaperone FliS; InterPro IPR003713; KEGG: sta:STHERM_c02390 flagellar protein FliS; PFAM: Flagellar protein FliS; SPTR: Putative flagellar protein FliS; TIGRFAM: Flagellar protein FliS.
 
 
 0.957
AEJ61215.1
PFAM: Flagellar hook-length control protein FliK; InterPro IPR001635; KEGG: sta:STHERM_c09160 hypothetical protein; PFAM: Flagellar hook-length control protein; SPTR: Flagellar hook-length control protein-like, C-terminal domain.
 
  
 0.957
AEJ61217.1
PFAM: Flagella basal body rod protein; Domain of unknown function (DUF1078); Flagellar basal body protein FlaE; TIGRFAM: fagellar hook-basal body proteins; COGs: COG1749 Flagellar hook protein FlgE; InterPro IPR001444:IPR011491:IPR010930:IPR020013; KEGG: sta:STHERM_c09180 flagellar hook protein; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellar basal body FlaE; Flagellar basal body rod protein, N-terminal; SPTR: Fagellar hook-basal body protein; TIGRFAM: Fagellar hook-basal body protein, FlgE/F/G.
 
  
 0.957
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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