STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
csrACarbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (77 aa)    
Predicted Functional Partners:
fliW
Flagellar assembly factor fliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
 
 0.998
AEJ61668.1
Flagellar hook-associated protein FlgK; PFAM: Flagellin hook IN motif; Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK; COGs: COG1256 Flagellar hook-associated protein; InterPro IPR010810:IPR010930:IPR002371; KEGG: sta:STHERM_c07620 flagellar hook-associated protein; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellin hook, IN motif; SPTR: Flagellar hook-associated protein FlgK; TIGRFAM: Flagellar hook-associated protein, FlgK.
 
  
 0.901
AEJ61667.1
Flagellar hook-associated protein 3; PFAM: Bacterial flagellin N-terminal helical region; Flagellin hook IN motif; TIGRFAM: flagellar hook-associated protein 3; COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001492:IPR010810:IPR013384; KEGG: sta:STHERM_c07630 hypothetical protein; PFAM: Flagellin, N-terminal; Flagellin hook, IN motif; SPTR: Flagellar hook-associated protein 3; TIGRFAM: Flagellar hook-associated protein 3.
 
  
 0.885
AEJ61669.1
PFAM: FlgN protein; KEGG: sta:STHERM_c07610 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.767
AEJ61223.1
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
  
   0.629
AEJ60509.1
PFAM: Flagellar protein FliS; TIGRFAM: flagellar biosynthetic protein FliS; COGs: COG1516 Flagellin-specific chaperone FliS; InterPro IPR003713; KEGG: sta:STHERM_c02390 flagellar protein FliS; PFAM: Flagellar protein FliS; SPTR: Putative flagellar protein FliS; TIGRFAM: Flagellar protein FliS.
 
  
 0.607
AEJ61209.1
Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
  
  
 0.603
glgA
Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
     
 0.574
AEJ61659.1
Flagellar hook-associated 2 domain-containing protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
  
 0.568
AEJ61674.1
PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase; COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR005835:IPR001451; KEGG: sta:STHERM_c07550 glucose-1-phosphate adenylyltransferase; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide repeat; SPTR: Glucose-1-phosphate adenylyltransferase.
     
 0.535
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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