STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61667.1Flagellar hook-associated protein 3; PFAM: Bacterial flagellin N-terminal helical region; Flagellin hook IN motif; TIGRFAM: flagellar hook-associated protein 3; COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001492:IPR010810:IPR013384; KEGG: sta:STHERM_c07630 hypothetical protein; PFAM: Flagellin, N-terminal; Flagellin hook, IN motif; SPTR: Flagellar hook-associated protein 3; TIGRFAM: Flagellar hook-associated protein 3. (415 aa)    
Predicted Functional Partners:
AEJ61668.1
Flagellar hook-associated protein FlgK; PFAM: Flagellin hook IN motif; Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK; COGs: COG1256 Flagellar hook-associated protein; InterPro IPR010810:IPR010930:IPR002371; KEGG: sta:STHERM_c07620 flagellar hook-associated protein; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellin hook, IN motif; SPTR: Flagellar hook-associated protein FlgK; TIGRFAM: Flagellar hook-associated protein, FlgK.
 
  
 0.987
fliW
Flagellar assembly factor fliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
 
 0.969
AEJ60509.1
PFAM: Flagellar protein FliS; TIGRFAM: flagellar biosynthetic protein FliS; COGs: COG1516 Flagellin-specific chaperone FliS; InterPro IPR003713; KEGG: sta:STHERM_c02390 flagellar protein FliS; PFAM: Flagellar protein FliS; SPTR: Putative flagellar protein FliS; TIGRFAM: Flagellar protein FliS.
 
 
 0.967
AEJ61223.1
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
 
 
 0.966
AEJ61659.1
Flagellar hook-associated 2 domain-containing protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
 
 0.927
AEJ61206.1
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
 
 
 0.918
AEJ61222.1
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
  
 0.916
AEJ61217.1
PFAM: Flagella basal body rod protein; Domain of unknown function (DUF1078); Flagellar basal body protein FlaE; TIGRFAM: fagellar hook-basal body proteins; COGs: COG1749 Flagellar hook protein FlgE; InterPro IPR001444:IPR011491:IPR010930:IPR020013; KEGG: sta:STHERM_c09180 flagellar hook protein; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellar basal body FlaE; Flagellar basal body rod protein, N-terminal; SPTR: Fagellar hook-basal body protein; TIGRFAM: Fagellar hook-basal body protein, FlgE/F/G.
 
  
 0.910
AEJ61208.1
PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE; COGs: COG1677 Flagellar hook-basal body protein; InterPro IPR001624; KEGG: sta:STHERM_c09090 flagellar hook-basal body complex protein FliE; PFAM: Flagellar hook-basal body complex protein FliE; SPTR: Flagellar hook-basal body complex subunit FliE; TIGRFAM: Flagellar hook-basal body complex protein FliE.
 
 
 0.907
AEJ61209.1
Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
 
  
 0.900
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.