Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61669.1PFAM: FlgN protein; KEGG: sta:STHERM_c07610 hypothetical protein; SPTR: Putative uncharacterized protein. (163 aa)    
Predicted Functional Partners:
AEJ61668.1
Flagellar hook-associated protein FlgK; PFAM: Flagellin hook IN motif; Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK; COGs: COG1256 Flagellar hook-associated protein; InterPro IPR010810:IPR010930:IPR002371; KEGG: sta:STHERM_c07620 flagellar hook-associated protein; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellin hook, IN motif; SPTR: Flagellar hook-associated protein FlgK; TIGRFAM: Flagellar hook-associated protein, FlgK.
       0.773
csrA
Carbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
       0.767
fliW
Flagellar assembly factor fliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
       0.767
AEJ61667.1
Flagellar hook-associated protein 3; PFAM: Bacterial flagellin N-terminal helical region; Flagellin hook IN motif; TIGRFAM: flagellar hook-associated protein 3; COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001492:IPR010810:IPR013384; KEGG: sta:STHERM_c07630 hypothetical protein; PFAM: Flagellin, N-terminal; Flagellin hook, IN motif; SPTR: Flagellar hook-associated protein 3; TIGRFAM: Flagellar hook-associated protein 3.
       0.767
AEJ61670.1
Thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase; COGs: COG0492 Thioredoxin reductase; InterPro IPR013027:IPR005982; KEGG: sta:STHERM_c07590 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: Thioredoxin reductase.
       0.511
AEJ61671.1
PFAM: Glycosyl hydrolase family 3 N terminal domain; COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764; KEGG: sta:STHERM_c07580 hypothetical protein; PFAM: Glycoside hydrolase, family 3, N-terminal; SPTR: Glycoside hydrolase family 3 domain protein.
       0.511
AEJ61672.1
GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family; COGs: COG3393 acetyltransferase; InterPro IPR000182; KEGG: sta:STHERM_c07570 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase.
       0.511
glgA
Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
       0.471
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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