Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61670.1Thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase; COGs: COG0492 Thioredoxin reductase; InterPro IPR013027:IPR005982; KEGG: sta:STHERM_c07590 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: Thioredoxin reductase. (316 aa)    
Predicted Functional Partners:
AEJ60457.1
PFAM: Thioredoxin; TIGRFAM: thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766:IPR005746; KEGG: sta:STHERM_c01860 thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: Thioredoxin; Belongs to the thioredoxin family.
 
 0.981
AEJ60874.1
Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
 
  0.907
AEJ60537.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.868
AEJ60402.1
PFAM: Thioredoxin; TIGRFAM: thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766:IPR005746; KEGG: sta:STHERM_c01270 thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: Thioredoxin; Belongs to the thioredoxin family.
 
 
 0.825
AEJ61442.1
TIGRFAM: small redox-active disulfide protein 2; InterPro IPR005243; KEGG: sta:STHERM_c11400 redox-active disulfide protein 2; SPTR: Redox-active disulfide protein 2; TIGRFAM: Redox-active disulphide protein 2.
  
 
 0.790
AEJ61672.1
GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family; COGs: COG3393 acetyltransferase; InterPro IPR000182; KEGG: sta:STHERM_c07570 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase.
       0.787
AEJ61671.1
PFAM: Glycosyl hydrolase family 3 N terminal domain; COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764; KEGG: sta:STHERM_c07580 hypothetical protein; PFAM: Glycoside hydrolase, family 3, N-terminal; SPTR: Glycoside hydrolase family 3 domain protein.
       0.776
glgA
Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
       0.711
AEJ62212.1
Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; COGs: COG2236 phosphoribosyltransferase; InterPro IPR000836; KEGG: sta:STHERM_c19080 hypothetical protein; PFAM: Phosphoribosyltransferase; SPTR: Putative uncharacterized protein.
  
     0.606
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.592
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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