Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61677.1KEGG: sta:STHERM_c07520 hypothetical protein; SPTR: Putative uncharacterized protein. (184 aa)    
Predicted Functional Partners:
nnrD
YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family.
       0.796
AEJ61679.1
Lipoprotein; KEGG: sta:STHERM_c07490 lipoprotein; SPTR: Putative uncharacterized protein.
       0.777
AEJ61675.1
PFAM: NUDIX domain; TIGRFAM: mutator mutT protein; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086; KEGG: sta:STHERM_c07540 hypothetical protein; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase.
       0.741
AEJ61676.1
KEGG: sta:STHERM_c07530 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.741
secA
Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
       0.554
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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