STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nnrDYjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. (491 aa)    
Predicted Functional Partners:
AEJ60443.1
PFAM: NUDIX domain; InterPro IPR000086; KEGG: sta:STHERM_c01680 hypothetical protein; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase.
  
 0.821
AEJ61640.1
PFAM: NUDIX domain; InterPro IPR000086; KEGG: sta:STHERM_c07930 hypothetical protein; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase.
  
 0.821
AEJ61679.1
Lipoprotein; KEGG: sta:STHERM_c07490 lipoprotein; SPTR: Putative uncharacterized protein.
       0.815
AEJ61677.1
KEGG: sta:STHERM_c07520 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.800
AEJ61676.1
KEGG: sta:STHERM_c07530 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.786
AEJ61091.1
ATP-dependent RNA helicase RhlB; PFAM: DEAD/DEAH box helicase; COGs: COG0513 Superfamily II DNA and RNA helicase; KEGG: sta:STHERM_c14160 ATP-dependent RNA helicase RhlB; SPTR: Putative uncharacterized protein.
  
 0.775
AEJ61988.1
PFAM: DbpA RNA binding domain; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR005580; KEGG: sta:STHERM_c16690 hypothetical protein; PFAM: DbpA, RNA-binding; SPTR: DbpA RNA-binding domain protein.
  
 0.775
AEJ61675.1
PFAM: NUDIX domain; TIGRFAM: mutator mutT protein; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086; KEGG: sta:STHERM_c07540 hypothetical protein; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase.
       0.759
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
   0.743
AEJ61663.1
Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: sta:STHERM_c07670 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Uncharacterized protein family UPF0079, ATPase; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria.
  
 
 0.694
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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