Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61698.1PFAM: ABC transporter; COGs: COG1127 ABC-type transport system involved in resistance to organic solvents ATPase component; InterPro IPR003593:IPR003439; KEGG: sta:STHERM_c07220 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein. (270 aa)    
Predicted Functional Partners:
AEJ61697.1
PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein; COGs: COG0767 ABC-type transport system involved in resistance to organic solvents permease component; InterPro IPR003453; KEGG: sta:STHERM_c07230 transporter; PFAM: Protein of unknown function DUF140; SPTR: Putative uncharacterized protein.
 
  
 0.964
AEJ61699.1
Mammalian cell entry related domain protein; PFAM: mce related protein; COGs: COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: sta:STHERM_c07210 hypothetical protein; PFAM: Mammalian cell entry related; SPTR: Mammalian cell entry related domain protein.
    
 0.959
AEJ61700.1
Tetratricopeptide TPR_2 repeat-containing protein; InterPro IPR019734:IPR013105:IPR001440; KEGG: sta:STHERM_c07200 hypothetical protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
       0.804
AEJ61702.1
PFAM: Peptidase family M23; LysM domain; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR018392:IPR016047; KEGG: sta:STHERM_c07180 M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SPTR: Peptidase M23.
       0.787
AEJ61703.1
PFAM: PEGA domain; InterPro IPR013229; KEGG: sta:STHERM_c07170 hypothetical protein; PFAM: PEGA; SPTR: PEGA domain protein.
       0.777
AEJ61696.1
PFAM: PHP domain; COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR003141:IPR004013; KEGG: sta:STHERM_c07240 hypothetical protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: PHP domain protein.
       0.774
AEJ61701.1
KEGG: sta:STHERM_c07190 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ62459.1
PFAM: Methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form; COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR004620:IPR003171; KEGG: sta:STHERM_c21610 5,10-methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase.
   
  
 0.751
AEJ62020.1
PFAM: ABC transporter; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: sta:STHERM_c16870 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
  
     0.726
AEJ60923.1
PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367; KEGG: sta:STHERM_c06290 iron-dependent repressor; PFAM: Iron dependent repressor; SMART: Iron dependent repressor; SPTR: Iron (Metal) dependent repressor, DtxR family.
   
   0.695
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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