STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61705.1Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460:IPR011816; KEGG: sta:STHERM_c07150 penicillin-binding protein; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; SPTR: Penicillin-binding protein, 1A family; TIGRFAM: Penicillin-binding protein 1A. (844 aa)    
Predicted Functional Partners:
AEJ62110.1
PFAM: D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5, C-terminal domain; COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR001967:IPR012907; KEGG: sta:STHERM_c17820 D-alanyl-D-alanine carboxypeptidase A; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; SPTR: Serine-type D-Ala-D-Ala carboxypeptidase.
  
  
 0.930
AEJ60360.1
PFAM: Penicillin-Binding Protein C-terminus Family; Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein 1C; COGs: COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; InterPro IPR001264:IPR001460:IPR009647:IPR011815; KEGG: sta:STHERM_c00860 hypothetical protein; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; Penicillin-binding, C-terminal; SPTR: Penicillin-binding protein 1C; TIGRFAM: Penicillin-binding protein 1C.
  
  
0.926
AEJ61960.1
Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; PFAM: D-alanyl-D-alanine carboxypeptidase; COGs: COG1876 D-alanyl-D-alanine carboxypeptidase; InterPro IPR003709; KEGG: sta:STHERM_c16390 hypothetical protein; PFAM: Peptidase M15B/M15C, D,D-carboxypeptidase VanY/endolysins; SPTR: Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin.
  
  
  0.912
AEJ61388.1
Penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460:IPR017790; KEGG: sta:STHERM_c10880 penicillin-binding protein; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; SPTR: Penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2.
 
 
 
 0.777
AEJ61706.1
PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; InterPro IPR003115; KEGG: sta:STHERM_c07140 ParB-like nuclease domain-containing protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: ParB domain protein nuclease.
 
     0.725
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
   
 0.724
AEJ61683.1
PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543:IPR005311:IPR001460; KEGG: sta:STHERM_c07450 penicillin-binding protein; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA; SMART: PASTA; SPTR: Peptidoglycan glycosyltransferase.
 
 
 
 0.710
AEJ62165.1
PFAM: Peptidase family M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: sta:STHERM_c18630 M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; SPTR: Peptidase M23.
 
   
 0.690
AEJ61195.1
PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182:IPR013437; KEGG: sta:STHERM_c08960 hypothetical protein; PFAM: Cell cycle protein; SPTR: Cell division protein FtsW; TIGRFAM: Cell division protein FtsW; Belongs to the SEDS family.
  
   
 0.684
AEJ61682.1
PFAM: Peptidase family M23; LysM domain; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR002482:IPR018392:IPR016047; KEGG: sta:STHERM_c07460 hypothetical protein; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Peptidase M23.
 
   
 0.659
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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