STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61706.1PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; InterPro IPR003115; KEGG: sta:STHERM_c07140 ParB-like nuclease domain-containing protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: ParB domain protein nuclease. (134 aa)    
Predicted Functional Partners:
AEJ60348.1
Cobyrinic acid ac-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; COGs: COG0455 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: sta:STHERM_c00750 hypothetical protein; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Putative uncharacterized protein.
 
 
 0.774
AEJ62547.1
Cobyrinic acid ac-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: sta:STHERM_c22520 hypothetical protein; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Putative uncharacterized protein.
 
 
 0.767
AEJ62479.1
Cobyrinic acid ac-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: sta:STHERM_c21780 cobyrinic acid a,c-diamide synthase; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: ParaA family ATPase.
 
 
 0.740
AEJ61705.1
Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460:IPR011816; KEGG: sta:STHERM_c07150 penicillin-binding protein; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; SPTR: Penicillin-binding protein, 1A family; TIGRFAM: Penicillin-binding protein 1A.
 
     0.725
rsmG
Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
  
 0.664
AEJ62546.1
parB-like partition protein; PFAM: Helix-turn-helix; ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; COGs: COG1475 transcriptional regulator protein; InterPro IPR004437:IPR003115; KEGG: sta:STHERM_c22510 chromosome 1-partitioning protein ParB; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: ParB-like partition protein; TIGRFAM: ParB-like partition protein.
  
   
 0.460
AEJ61704.1
PFAM: Protein of unknown function (DUF548); InterPro IPR007536; KEGG: sta:STHERM_c07160 hypothetical protein; PFAM: Protein of unknown function DUF548; SPTR: Putative uncharacterized protein.
       0.439
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.425
greA
Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
  
 
 
 0.409
AEJ62173.1
KEGG: sta:STHERM_c18710 cytoskeletal protein; SPTR: Putative uncharacterized protein.
 
 
 0.408
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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