Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61713.1PFAM: Bacterial extracellular solute-binding protein; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c07070 transporter; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Carbohydrate ABC transporter substrate-binding protein, CUT1 family. (418 aa)    
Predicted Functional Partners:
AEJ61714.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: sta:STHERM_c07060 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 1, CUT1 family.
 
  0.986
AEJ61715.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: sta:STHERM_c07050 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 2, CUT1 family.
 
  0.986
AEJ60469.1
PFAM: ABC transporter; TOBE domain; COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR003439:IPR013611:IPR003593; KEGG: sta:STHERM_c01980 sugar ABC transporter; PFAM: ABC transporter-like; Transport-associated OB, type 2; SMART: ATPase, AAA+ type, core; SPTR: Carbohydrate ABC transporter ATP-binding protein, CUT1 family.
  
 0.909
AEJ61494.1
PFAM: ABC transporter; COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR003593:IPR003439:IPR013611; KEGG: sta:STHERM_c11860 transporter; PFAM: ABC transporter-like; Transport-associated OB, type 2; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
  
 0.909
AEJ60998.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: sta:STHERM_c15020 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component.
  
   0.594
AEJ60997.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: sta:STHERM_c15030 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Glucosylglycerol ABC transporter membrane protein.
  
   0.535
AEJ60939.1
PFAM: Bacterial extracellular solute-binding protein; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: sta:STHERM_c06450 transporter; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Extracellular solute-binding protein family 1.
  
     0.520
AEJ61592.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: sta:STHERM_c08450 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 2, CUT1 family.
 
 
 0.506
AEJ61712.1
Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: sta:STHERM_c07080 transcriptional regulatory protein; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver region; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver r [...]
   
   0.470
AEJ62358.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: ttr:Tter_2658 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 1, CUT1 family.
  
   0.469
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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