STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AEJ61716.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (472 aa)    
Predicted Functional Partners:
AEJ61717.1
PFAM: Isochorismatase family; COGs: COG1335 Amidase related to nicotinamidase; InterPro IPR000868; KEGG: sta:STHERM_c07030 hypothetical protein; PFAM: Isochorismatase-like; SPTR: Nicotinamidase.
 
 0.998
AEJ61335.1
Nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR002638:IPR004393; KEGG: sta:STHERM_c10350 hypothetical protein; PFAM: Quinolinate phosphoribosyl transferase; SPTR: Nicotinate-nucleotide pyrophosphorylase; TIGRFAM: Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
   
 0.942
AEJ62297.1
Competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR001453:IPR008136:IPR008135; KEGG: sta:STHERM_c19900 CinA-like protein; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; CinA, C-terminal.
  
 
 0.942
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.937
AEJ62523.1
PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD); COGs: COG0813 Purine-nucleoside phosphorylase; HAMAP: Purine nucleoside phosphorylase deoD-type; InterPro IPR004402:IPR000845; KEGG: sta:STHERM_c22230 purine nucleoside phosphorylase DeoD-type; PFAM: Nucleoside phosphorylase; SPTR: Purine-nucleoside phosphorylase; TIGRFAM: Purine nucleoside phosphorylase.
     
 0.912
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.902
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.634
AEJ61535.1
PFAM: Bacterial capsule synthesis protein PGA_cap; COGs: COG2843 Putative protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: sta:STHERM_c12320 hypothetical protein; PFAM: Capsule synthesis protein, CapA; SPTR: Capsule synthesis protein, CapA.
  
    0.600
AEJ62509.1
PFAM: Bacterial capsule synthesis protein PGA_cap; COGs: COG2843 Putative protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: sta:STHERM_c22100 hypothetical protein; PFAM: Capsule synthesis protein, CapA; SPTR: Capsule synthesis protein, CapA.
  
    0.600
AEJ61714.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: sta:STHERM_c07060 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 1, CUT1 family.
       0.532
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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