Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61718.1PFAM: von Willebrand factor type A domain; InterPro IPR002035; KEGG: sta:STHERM_c06990 hypothetical protein; PFAM: von Willebrand factor, type A; SMART: von Willebrand factor, type A; SPTR: von Willebrand factor type A. (459 aa)    
Predicted Functional Partners:
AEJ61721.1
KEGG: sta:STHERM_c06960 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.916
AEJ61719.1
Forkhead-associated protein; PFAM: FHA domain; InterPro IPR000253; KEGG: sta:STHERM_c06980 hypothetical protein; PFAM: Forkhead-associated; SPTR: Forkhead-associated protein.
      0.896
AEJ61723.1
PFAM: Bacterial DNA-binding protein; COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: sta:STHERM_c06940 hypothetical protein; PFAM: Histone-like bacterial DNA-binding protein; SMART: Histone-like bacterial DNA-binding protein; SPTR: Histone family protein DNA-binding protein.
 
     0.853
AEJ61720.1
PFAM: Protein kinase domain; COGs: COG0515 Serine/threonine protein kinase; InterPro IPR020635:IPR002290:IPR017442; KEGG: sta:STHERM_c06970 serine/threonine-protein kinase Sps1; PFAM: Serine/threonine-protein kinase-like domain; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, subgroup, catalytic domain; SPTR: Serine/threonine protein kinase.
 
     0.828
AEJ61722.1
KEGG: sta:STHERM_c06950 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.796
AEJ61998.1
PFAM: von Willebrand factor type A domain; InterPro IPR002035; KEGG: sta:STHERM_c16780 BatA protein; PFAM: von Willebrand factor, type A; SMART: von Willebrand factor, type A; SPTR: von Willebrand factor type A.
  
     0.619
AEJ62000.1
Von Willebrand factor type A; PFAM: Protein of unknown function DUF58; COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor type A (vWA) domain); InterPro IPR002035:IPR002881; KEGG: sta:STHERM_c16800 MoxR protein; PFAM: von Willebrand factor, type A; Protein of unknown function DUF58; SMART: von Willebrand factor, type A; SPTR: von Willebrand factor type A.
 
    0.611
AEJ61997.1
PFAM: von Willebrand factor type A domain; InterPro IPR002035; KEGG: sta:STHERM_c16770 von Willebrand factor type A; PFAM: von Willebrand factor, type A; SMART: von Willebrand factor, type A; SPTR: von Willebrand factor type A.
  
     0.589
AEJ61379.1
OmpA/MotB domain protein; PFAM: OmpA family; COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: sta:STHERM_c10790 OmpA family protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; SPTR: OmpA/MotB domain protein.
  
     0.576
AEJ60686.1
PFAM: Tetratricopeptide repeat; Protein of unknown function (DUF1570); InterPro IPR019734:IPR013105:IPR001440; KEGG: sta:STHERM_c04360 hypothetical protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
     0.565
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.