STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61722.1KEGG: sta:STHERM_c06950 hypothetical protein; SPTR: Putative uncharacterized protein. (174 aa)    
Predicted Functional Partners:
AEJ61721.1
KEGG: sta:STHERM_c06960 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.811
AEJ61720.1
PFAM: Protein kinase domain; COGs: COG0515 Serine/threonine protein kinase; InterPro IPR020635:IPR002290:IPR017442; KEGG: sta:STHERM_c06970 serine/threonine-protein kinase Sps1; PFAM: Serine/threonine-protein kinase-like domain; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, subgroup, catalytic domain; SPTR: Serine/threonine protein kinase.
     
 0.802
AEJ61718.1
PFAM: von Willebrand factor type A domain; InterPro IPR002035; KEGG: sta:STHERM_c06990 hypothetical protein; PFAM: von Willebrand factor, type A; SMART: von Willebrand factor, type A; SPTR: von Willebrand factor type A.
       0.801
AEJ61719.1
Forkhead-associated protein; PFAM: FHA domain; InterPro IPR000253; KEGG: sta:STHERM_c06980 hypothetical protein; PFAM: Forkhead-associated; SPTR: Forkhead-associated protein.
       0.799
AEJ61723.1
PFAM: Bacterial DNA-binding protein; COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: sta:STHERM_c06940 hypothetical protein; PFAM: Histone-like bacterial DNA-binding protein; SMART: Histone-like bacterial DNA-binding protein; SPTR: Histone family protein DNA-binding protein.
      
0.590
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
  
 0.558
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
  
 0.477
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
    0.459
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.410
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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